Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.31 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5492047 | 0.85 | KMT2A (0.34) | TRPA1LMNACHRM1SLC6A2ADRA1A | |
| SCHEMBL7614292 | 0.77 | ESR1 (0.42) | LMNACHRM1SLC6A2ADRA1AHTR2B | |
| SCHEMBL28263806 | 0.76 | TSHR (0.42) | CASRTRPA1LMNACHRM1SLC6A2 | |
| SCHEMBL9688997 | 0.76 | SRC (0.41) | CASRTRPA1LMNACHRM1SLC6A2 | |
| SCHEMBL20738712 | 0.75 | TRPA1 (0.45) | CASRTRPA1LMNACHRM1SLC6A2 | |
| SCHEMBL9090921 | 0.74 | TRPA1 (0.37) | CASRTRPA1LMNACHRM1SLC6A2 | |
| SCHEMBL28599084 | 0.73 | KDM4E (0.40) | CASRTRPA1LMNACHRM1SLC6A2 | |
| SCHEMBL5494536 | 0.72 | ACHE (0.44) | LMNATDP1ALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL15919018 | 0.72 | SRC (0.41) | CASRTRPA1LMNACHRM1SLC6A2 | |
| SCHEMBL8996446 | 0.72 | NR3C1 (0.44) | CASRTRPA1LMNACHRM1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7291747-B2 | Silicon compounds and process for preparation thereof | CHISSO CORPORATION (JP) | 2007-11-06 | — | — | US | disclosed |
| US-20040143081-A1 | Novel silicon compounds and process for preparation thereof | JNC CORPORATION (JP) | 2004-07-22 | — | — | US | disclosed |