Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 11/20 | 0.54 |
| ▸ | MMP3 | P08254 | 8/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 3/20 | 0.41 |
| ▸ | SLC15A1 | P46059 | 2/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL7669601 | 1.00 | MMP2 (0.54) | MMP2MMP3POLBLTA4HSLC15A1 | |
| Trifluoroacetic Acid SCHEMBL7606327 | 0.88 | MMP3 (0.48) | MMP2MMP3SLC15A1MMP1MMP9 | |
| Trifluoroacetic Acid SCHEMBL7405960 | 0.88 | MMP3 (0.48) | MMP2MMP3SLC15A1MMP1MMP9 | |
| SCHEMBL7412193 | 0.82 | MMP3 (0.53) | MMP2MMP3SLC15A1MMP1MMP9 | |
| SCHEMBL7672661 | 0.82 | MMP3 (0.53) | MMP2MMP3SLC15A1MMP1MMP9 | |
| SCHEMBL7403675 | 0.82 | MMP2 (0.54) | MMP2MMP3POLBMMP9 | |
| SCHEMBL7403678 | 0.82 | MMP2 (0.54) | MMP2MMP3POLBMMP9 | |
| Trifluoroacetic Acid SCHEMBL7413892 | 0.79 | SLC15A1 (0.45) | SLC15A1MMP1MMP9 | |
| Trifluoroacetic Acid SCHEMBL7608053 | 0.79 | SLC15A1 (0.45) | SLC15A1MMP1MMP9 | |
| SCHEMBL7447895 | 0.76 | MMP2 (0.49) | MMP2MMP3POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6495699-B2 | ANTIARTHRITIC AGENTS; OSTEOPOROSIS | AGOURON PHARMACEUTICALS INC. | 2002-12-17 | — | — | US | disclosed |
| US-20020019429-A1 | Metalloproteinase inhibitors, pharmaceutical compositions containing them, and their use | BENDER STEVEN L (US) | 2002-02-14 | — | — | US | disclosed |
| US-6306892-B1 | ENZYME INHIBITORS HETEROCYCLIC AMIDES | AGOURON PHARMACEUTICALS, INC. | 2001-10-23 | — | — | US | disclosed |
| US-6174915-B1 | FOR TREATING MAMMALIAN DISEASE CONDITION MEDIATED BY METALLOPROTEINASE ACTIVITY | AGOURON PHARMACEUTICALS, INC. | 2001-01-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020019429-A1 | Metalloproteinase inhibitors, pharmaceutical compositions containing them, and their use | MMP9, MMP2, MMP3 | MMP2 2/4885MMP3 3/4885POLB 2433/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.