⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3482717 | 0.84 | ALDH1A1 (0.31) | — | |
| SCHEMBL1996617 | 0.71 | ALDH1A1 (0.31) | — | |
| SCHEMBL4073190 | 0.68 | — | — | |
| SCHEMBL3481762 | 0.67 | ALDH1A1 (0.30) | — | |
| SCHEMBL3481862 | 0.66 | DNM1 (0.35) | — | |
| SCHEMBL3481471 | 0.64 | OPRM1 (0.42) | — | |
| SCHEMBL2769582 | 0.64 | — | — | |
| SCHEMBL8139612 | 0.63 | OPRM1 (0.41) | — | |
| SCHEMBL7980222 | 0.63 | TSHR (0.43) | — | |
| SCHEMBL3974159 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6423858-B1 | REACTING ORGANOSILANE WITH AMMONIA OR ORGANIC AMINE COMPOUND, EVAPORATING AMMONIA OR ORGANIC AMINE UNDER REDUCED PRESSURE, ALLOWING AMMONIUM CHLORIDE OR AMINOHYDROCHLORIDE BY-PRODUCTS TO CRYSTALLIZE AND SEPARATE, DISTILLING PRODUCT | DEGUSSA AG (DE) | 2002-07-23 | — | — | US | claimed |
| US-20020065428-A1 | MANUFACTURING PROCESS FOR AMINOALKYL SILANES | DEGUSSA AG (DE) | 2002-05-30 | — | — | US | claimed |
| US-6423858-B1 | REACTING ORGANOSILANE WITH AMMONIA OR ORGANIC AMINE COMPOUND, EVAPORATING AMMONIA OR ORGANIC AMINE UNDER REDUCED PRESSURE, ALLOWING AMMONIUM CHLORIDE OR AMINOHYDROCHLORIDE BY-PRODUCTS TO CRYSTALLIZE AND SEPARATE, DISTILLING PRODUCT | DEGUSSA AG (DE) | 2002-07-23 | — | — | US | disclosed |
| US-20020065428-A1 | MANUFACTURING PROCESS FOR AMINOALKYL SILANES | DEGUSSA AG (DE) | 2002-05-30 | — | — | US | disclosed |