Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3481885 | 0.88 | DNM1 (0.39) | TSHRTDP1ALDH1A1DNM1 | |
| SCHEMBL28753770 | 0.84 | — | — | |
| SCHEMBL705781 | 0.83 | DNM1 (0.36) | TSHRTDP1ALDH1A1DNM1 | |
| SCHEMBL3482199 | 0.83 | DNM1 (0.42) | TSHRDNM1 | |
| SCHEMBL3481447 | 0.81 | DNM1 (0.46) | TSHRDNM1 | |
| SCHEMBL27323251 | 0.81 | DNM1 (0.46) | TSHRDNM1 | |
| SCHEMBL11210376 | 0.81 | DNM1 (0.46) | TSHRDNM1 | |
| SCHEMBL4770413 | 0.80 | OPRM1 (0.42) | TSHRDNM1 | |
| SCHEMBL4766710 | 0.78 | LMNA (0.42) | TSHRDNM1 | |
| SCHEMBL7056921 | 0.78 | LMNA (0.42) | TSHRDNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5834536-A | REACTING HALOGENATED ALKYL SILANE WITH INORGANIC POLYSULFIDE IN PRESENCE OF WATER AND FILLER(CARRIER) FIBERS OR PARTICLES, THEN DRYING BEFORE MIXING INTO RUBBER; FOR HEAT RESISTANT TIRES HAVING LOW ROLLING RESISTANCE | BAYER AG (DE) | 1998-11-10 | — | — | US | claimed |
| US-6277902-B1 | RUBBER COMPOUNDS COMPRISING SOLUBLE RUBBER, HYDROPHOBIZED FILLER HAVING SPECIFIED METHANOL WETTABILITY, SUPPORTEDPOLYSULFIDIC-SILANE COMPOUNDS PREPARED BY REACTION OF HALOALKYLSILANES, ORGANIC HALOGEN COMPOUNDS AND POLYSULFIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2001-08-21 | — | — | US | disclosed |
| US-5834536-A | REACTING HALOGENATED ALKYL SILANE WITH INORGANIC POLYSULFIDE IN PRESENCE OF WATER AND FILLER(CARRIER) FIBERS OR PARTICLES, THEN DRYING BEFORE MIXING INTO RUBBER; FOR HEAT RESISTANT TIRES HAVING LOW ROLLING RESISTANCE | BAYER AG (DE) | 1998-11-10 | — | — | US | disclosed |
| US-5770754-A | Method of preparing polysulphidic silyl ethers | BAYER AKTIENGESELLSCHAFT (DE) | 1998-06-23 | — | — | US | disclosed |