Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | UGT2B7 | P16662 | 1/20 | 0.37 |
| ▸ | NOS3 | P29474 | 1/20 | 0.35 |
| ▸ | NOS1 | P29475 | 1/20 | 0.35 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | FURIN | P09958 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | ACACB | O00763 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL394726 | 0.88 | ALDH1A1 (0.55) | ALDH1A1UGT2B7NOS3NOS1TDP1 | |
| SCHEMBL4941225 | 0.85 | UGT2B7 (0.46) | ALDH1A1UGT2B7NOS3NOS1SRD5A2 | |
| SCHEMBL7518854 | 0.82 | ALDH1A1 (0.48) | ALDH1A1UGT2B7NOS3NOS1TDP1 | |
| SCHEMBL296908 | 0.81 | ALDH1A1 (0.65) | ALDH1A1CHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL6743494 | 0.80 | RXRA (0.49) | CHRNB2CHRNB4CHRNA3CHRNA7CHRNA4 | |
| SCHEMBL17445753 | 0.79 | ALDH1A1 (0.41) | ALDH1A1CHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL4368301 | 0.78 | SRD5A2 (0.55) | ALDH1A1UGT2B7SRD5A2ACACBACACA | |
| SCHEMBL14222884 | 0.78 | ESR1 (0.61) | UGT2B7MEN1KMT2A | |
| SCHEMBL9923547 | 0.78 | TEAD4 (0.50) | ALDH1A1UGT2B7NOS3NOS1SRD5A2 | |
| SCHEMBL18383080 | 0.78 | LTA4H (0.56) | ALDH1A1TDP1TSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020007029-A1 | Novel polyester resins | ZAITSEY BORIS A (RU) | 2002-01-17 | — | — | US | disclosed |
| US-6258909-B1 | Polyester resins | ZAITSEV BORIS A (RU) | 2001-07-10 | — | — | US | disclosed |
| US-6143922-A | NOVEL DIOL COMPOSITIONS, NOVEL UNSATURATED MONOMERS, NOVEL RESINS, NOVEL CROSSLINKED POLYMERS, NOVEL POLYESTER POLYMERS, NOVEL POLYESTER POLYMERS THAT DISPLAY IMPROVEMENT OVER ROLIVSAN RESINS | ZAITSEV BORIS A (RU) | 2000-11-07 | — | — | US | disclosed |