Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 1/20 | 0.55 |
| ▸ | LTA4H | P09960 | 5/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.52 |
| ▸ | BAX | Q07812 | 1/20 | 0.52 |
| ▸ | ACACB | O00763 | 2/20 | 0.51 |
| ▸ | ACACA | Q13085 | 2/20 | 0.51 |
| ▸ | UGT2B7 | P16662 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8692147 | 0.98 | SRD5A2 (0.53) | SRD5A2LTA4HTSHRNR1H2BAX | |
| SCHEMBL4941225 | 0.91 | UGT2B7 (0.46) | SRD5A2LTA4HTSHRACACBACACA | |
| Diphenylether SCHEMBL29076650 | 0.84 | LTA4H (0.67) | SRD5A2LTA4HTSHRNR1H2BAX | |
| Diphenylether SCHEMBL11134302 | 0.84 | LTA4H (0.67) | SRD5A2LTA4HTSHRNR1H2BAX | |
| SCHEMBL11531206 | 0.83 | NPY5R (0.53) | SRD5A2LTA4HTSHRNR1H2BAX | |
| SCHEMBL28633577 | 0.83 | NPY5R (0.53) | SRD5A2LTA4HTSHRNR1H2BAX | |
| SCHEMBL14222884 | 0.83 | ESR1 (0.61) | LTA4HNR1H2BAXUGT2B7 | |
| SCHEMBL9923547 | 0.83 | TEAD4 (0.50) | SRD5A2UGT2B7ALDH1A1HTT | |
| SCHEMBL18383080 | 0.83 | LTA4H (0.56) | LTA4HTSHRCA1CA2ALDH1A1 | |
| SCHEMBL172607 | 0.82 | LTA4H (0.57) | SRD5A2LTA4HTSHRNR1H2BAX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140243547-A1 | LINEAR (PER) FLUOROPOLYETHERS WITH -CF(CF3)COF END GROUPS AND DERIVATIVES THEREOF | SOLVAY SPECIALTY POLYMERS ITALY S.P.A. (IT) | 2014-08-28 | — | — | US | disclosed |
| EP-2562165-A1 | 5-FLUORO PYRIMIDINE DERIVATIVES AS FUNGICIDES | Dow AgroSciences LLC (US) | 2013-02-27 | — | — | EP | disclosed |
| US-8278256-B2 | Fluorinated lubricants | SOLVAY SOLEXIS S.P.A. (IT) | 2012-10-02 | — | — | US | disclosed |
| US-8217119-B2 | Additives for halopolymers | SOLVAY SOLEXIS S.P.A. (IT) | 2012-07-10 | — | — | US | disclosed |
| US-20100069275-A1 | Fluorinated lubricants | SOLVAY SOLEXIS S.P.A. (IT) | 2010-03-18 | — | — | US | disclosed |
| US-20090326154-A1 | Additives for Halopolymers | SOLVAY SOLEXIS S.P.A. (IT) | 2009-12-31 | — | — | US | disclosed |
| US-7629483-B2 | Peroxidic perfluoropolyethers | SOLVAY SOLEXIS S.P.A. (IT) | 2009-12-08 | — | — | US | disclosed |
| EP-2055378-A1 | Method for preparing ruthenium-carrying alumina and method for oxidizing alcohol | Sumitomo Chemical Company, Limited (JP) | 2009-05-06 | — | — | EP | disclosed |
| EP-1500432-B1 | METHOD FOR OXIDIZING ALCOHOL ON A RUTHENIUM-CARRYING ALUMINA CATALYST | SUMITOMO CHEMICAL CO (JP) | 2009-04-22 | — | — | EP | disclosed |
| US-20080194881-A1 | Copolymers having functional end groups of sulfonyl fluorides and acyl fluorides; macromer promoters useful for both condensation and addition polymerizations for elastomers and polymershaving a crystal structure; mechanical properties; lubricants for magnetic disks; adhesives | SOLVAY SOLEXIS S.P.A. (IT) | 2008-08-14 | — | — | US | disclosed |
| US-7371900-B2 | Peroxidic perfluoropolyethers | SOLVAY SOLEXIS S.P.A. (IT) | 2008-05-13 | — | — | US | disclosed |
| US-7365229-B2 | Peroxidic perfluoropolyethers | SOLVAY SOLEXIS S.P.A. (IT) | 2008-04-29 | — | — | US | disclosed |
| US-7169954-B2 | Method for preparing ruthenium-carrying alumina and method for oxidizing alcohol | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-01-30 | — | — | US | disclosed |
| US-20060094899-A1 | Process for preparing ruthenium-carrying alumina and process for oxidizing alcohol | SUMITOMO CHEMICAL COMPANY, LIMITED | 2006-05-04 | — | — | US | disclosed |
| EP-1500432-A1 | METHOD FOR PREPARING RUTHENIUM-CARRYING ALUMINA AND METHOD FOR OXIDIZING ALCOHOL | Sumitomo Chemical Company, Limited (JP) | 2005-01-26 | — | — | EP | disclosed |
| US-20040204597-A1 | Method for preparing ruthenium-carrying alumina and method for oxidizing alcohol | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2004-10-14 | — | — | US | disclosed |
| US-5859020-A | INSECTICIDES, MITICIDES, FUNGICIDES, NEMATOCIDES | HOECHST SCHERING AGREVO GMBH (DE) | 1999-01-12 | — | — | US | disclosed |
| WO-1996034851-A1 | BENZENE, PYRIDINE, NAPHTALENE OR BENZOPHENONE DERIVATIVES AS INHIBITORS OF SQUALENE SYNTHETASE AND PROTEIN FARNESYLTRANSFERASE | ABBOTT LABORATORIES (US) | 1996-11-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140243547-A1 | LINEAR (PER) FLUOROPOLYETHERS WITH -CF(CF3)COF END GROUPS AND DERIVATIVES THEREOF | COXFA4, CYP4F3, ETFB | SRD5A2 3418/4885LTA4H 1995/4885TSHR 4515/4885 |
| US-20060094899-A1 | Process for preparing ruthenium-carrying alumina and process for oxidizing alcohol | ADH1A, ADH5, ADH7 | SRD5A2 353/4885LTA4H 1061/4885TSHR 2537/4885 |
| US-20040204597-A1 | Method for preparing ruthenium-carrying alumina and method for oxidizing alcohol | ADH1A, ADH7, ADH5 | SRD5A2 328/4885LTA4H 963/4885TSHR 2161/4885 |
| US-20080194881-A1 | Copolymers having functional end groups of sulfonyl fluorides and acyl fluorides; macromer promoters useful for both condensation and addition polymerizations for elastomers and polymershaving a crystal structure; mechanical properties; lubricants for magnetic disks; adhesives | FOXO1, FOXM1, F12 | SRD5A2 1480/4885LTA4H 4150/4885TSHR 1254/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.