SCHEMBL7609146

SCHEMBL7609146

NN(Cc1ccccn1)c1ccccn1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.55
SMN1; SMN2 Q16637 1/20 0.55
LIN28A Q9H9Z2 1/20 0.55
TDP1 Q9NUW8 1/20 0.55
HRH1 P35367 2/20 0.47
KCNA5 P22460 1/20 0.46
KMT2A Q03164 1/20 0.45
CYP2D6 P10635 1/20 0.42
CYP2C19 P33261 1/20 0.42
GRIN2D O15399 1/20 0.41
GRIN3B O60391 1/20 0.41
GRIN1 Q05586 1/20 0.41
GRIN2A Q12879 1/20 0.41
GRIN2B Q13224 1/20 0.41
GRIN2C Q14957 1/20 0.41
GRIN3A Q8TCU5 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
ALDH1A1 P00352 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
CHRNA7 P36544 3/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10806145 0.81 ALDH1A1 (0.54) SMN1; SMN2TDP1HRH1KMT2AL3MBTL1
SCHEMBL18301470 0.80 SMN1; SMN2 (0.59) MAPTSMN1; SMN2LIN28ATDP1HRH1
SCHEMBL230049 0.80 MAPT (0.64) MAPTSMN1; SMN2LIN28ATDP1HRH1
SCHEMBL17399715 0.79 MAPT (0.63) MAPTSMN1; SMN2LIN28ATDP1HRH1
SCHEMBL8815911 0.77 SMN1; SMN2 (0.55) MAPTSMN1; SMN2LIN28ATDP1HRH1
SCHEMBL18978312 0.76 SLC6A3 (0.38) MAPTSMN1; SMN2LIN28ATDP1HRH1
SCHEMBL2775015 0.76 CYP2D6 (0.48) SMN1; SMN2HRH1KCNA5CYP2D6CYP2C19
SCHEMBL31148356 0.75 TRPM8 (0.46) SMN1; SMN2TDP1HRH1KMT2ACYP2D6
SCHEMBL24152788 0.74 SMN1; SMN2 (0.68) MAPTSMN1; SMN2LIN28ATDP1HRH1
SCHEMBL138261 0.74 SMN1; SMN2 (0.83) MAPTSMN1; SMN2LIN28ATDP1HRH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2002089809-A1 MEDICINAL USES OF HYDRAZONES AND HYDRAZINES THE PROCTER & GAMBLE COMPANY (US) 2002-11-14 WO disclosed