Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | LIN28A | Q9H9Z2 | 1/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.64 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | HRH1 | P35367 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18301470 | 0.83 | SMN1; SMN2 (0.59) | MAPTSMN1; SMN2LIN28ATDP1CYP2D6 | |
| SCHEMBL230597 | 0.81 | CYP2D6 (0.47) | MAPTSMN1; SMN2LIN28ATDP1CYP2D6 | |
| SCHEMBL8815911 | 0.80 | SMN1; SMN2 (0.55) | MAPTSMN1; SMN2LIN28ATDP1CYP2D6 | |
| SCHEMBL1968010 | 0.80 | CYP2D6 (0.59) | MAPTSMN1; SMN2LIN28ATDP1CYP2D6 | |
| SCHEMBL7609146 | 0.80 | MAPT (0.55) | MAPTSMN1; SMN2LIN28ATDP1CYP2D6 | |
| SCHEMBL1444229 | 0.79 | CYP2D6 (0.53) | MAPTSMN1; SMN2LIN28ATDP1CYP2D6 | |
| SCHEMBL4370206 | 0.79 | MAPT (0.59) | MAPTSMN1; SMN2LIN28ATDP1KCNA5 | |
| SCHEMBL5609247 | 0.79 | ALDH1A1 (0.57) | SMN1; SMN2TDP1CYP2D6CYP2C19KMT2A | |
| SCHEMBL231092 | 0.78 | TDP1 (1.00) | MAPTSMN1; SMN2LIN28ATDP1KCNA5 | |
| SCHEMBL29427509 | 0.78 | TDP1 (1.00) | MAPTSMN1; SMN2LIN28ATDP1KCNA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8182718-B2 | Ligand exchange thermochromic systems and high ε ligands for same | PLEOTINT, L.L.C. (US) | 2012-05-22 | — | — | US | claimed |
| CN-101412694-A | Preparation of efficient green tripyridyl methyl amine compounds | UNIV JIANGSU (CN) | 2009-04-22 | — | — | CN | claimed |
| CN-119431673-A | Preparation method of extremely cold special oil product viscosity index improver | 新乡市瑞丰新材料股份有限公司 | 2025-02-14 | — | — | CN | disclosed |
| US-20240158426-A1 | TRANSITION METAL COMPLEX CONTAINING TETRADENTATE NITROGEN DONOR LIGAND AND ELECTROCHEMICAL BIOSENSOR COMPRISING SAME | I-SENS, INC. (KR) | 2024-05-16 | — | — | US | disclosed |
| CN-117821969-A | Polymer brush-based bionic super-slip coating and preparation method and application thereof | 中国科学院宁波材料技术与工程研究所 | 2024-04-05 | — | — | CN | disclosed |
| CN-115466340-B | Photosensitive component and its use in photoinitiated free radical polymerization | 东北林业大学 | 2024-03-26 | — | — | CN | disclosed |
| EP-4273152-A1 | TRANSITION METAL COMPLEX CONTAINING TETRADENTATE NITROGEN DONOR LIGAND AND ELECTROCHEMICAL BIOSENSOR COMPRISING SAME | I-SENS, INC. (KR) | 2023-11-08 | — | — | EP | disclosed |
| CN-114874674-B | Large-area hydrophilic polymer brush coating layer and preparation method and application thereof | 中国科学院宁波材料技术与工程研究所 | 2023-05-16 | — | — | CN | disclosed |
| CN-115466340-A | Photosensitive component and application thereof in photo-initiated free radical polymerization | 东北林业大学 | 2022-12-13 | — | — | CN | disclosed |
| CN-111057199-B | Aza-carbene-based nanogold surface polymer modification method | 青岛石控科技有限公司 | 2022-11-11 | — | — | CN | disclosed |
| CN-115010881-A | Oxygen-resistant and biocompatible metallic tin mediated initiated polymerization method and application | 中国科学院宁波材料技术与工程研究所 | 2022-09-06 | — | — | CN | disclosed |
| US-7538931-B2 | Ligand exchange thermochromic systems containing exchange metals | PLEOTINT, L.L.C. (US) | 2009-05-26 | — | — | US | disclosed |
| US-7525717-B2 | reversible; laminated; transition metal ion coordinated with a high epsilon ligand and a low epsilon ligand; polymer; separator; variable light transmission windows; polyvinyl butyral; nickel or cobalt iodide ligands; diol, triol or polyol ligands | PLEOTINT, L.L.C. (US) | 2009-04-28 | — | — | US | disclosed |
| CN-101412694-A | Preparation of efficient green tripyridyl methyl amine compounds | UNIV JIANGSU (CN) | 2009-04-22 | — | — | CN | disclosed |
| CN-101412694-A | Preparation of efficient green tripyridyl methyl amine compounds | UNIV JIANGSU (CN) | 2009-04-22 | — | — | CN | disclosed |
| US-20080105851-A1 | Exhibiting a reversible change in absorbance of electromagnetic radiation as the temperature of the system is reversibly changed; comprising a transition metal ion and a ligand | PLEOTINT, LLC (US) | 2008-05-08 | — | — | US | disclosed |
| US-20080106781-A1 | LIGAND EXCHANGE THERMOCHROMIC SYSTEMS CONTAINING EXCHANGE METALS | PLEOTINT, LLC (US) | 2008-05-08 | — | — | US | disclosed |
| US-20080100903-A1 | MULTI-LAYER LIGAND EXCHANGE THERMOCHROMIC SYSTEMS | PLEOTINT, LLC (US) | 2008-05-01 | — | — | US | disclosed |
| US-20080100902-A1 | LIGAND EXCHANGE THERMOCHROMIC, (LETC), SYSTEMS | PLEOTINT, LLC (US) | 2008-05-01 | — | — | US | disclosed |
| WO-2008028128-A1 | LIGAND EXCHANGE THERMOCHROMIC, (LETC), SYSTEMS | PLEOTINT, L.L.C. (US) | 2008-03-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240158426-A1 | TRANSITION METAL COMPLEX CONTAINING TETRADENTATE NITROGEN DONOR LIGAND AND ELECTROCHEMICAL BIOSENSOR COMPRISING SAME | NCS1, DNTT, SPR | MAPT 1426/4885SMN1; SMN2 3938/4885LIN28A 2813/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.