Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9129002 | 0.81 | HRH3 (0.43) | ACE2HRH3 | |
| SCHEMBL18712607 | 0.78 | ACE2 (0.31) | ACE2HRH3 | |
| SCHEMBL19616839 | 0.78 | TSHR (0.35) | ACE2HRH3 | |
| SCHEMBL17404736 | 0.78 | GNAI3 (0.44) | — | |
| SCHEMBL3973592 | 0.78 | KEAP1 (0.48) | ACE2 | |
| SCHEMBL4104385 | 0.78 | SIGMAR1 (0.38) | ACE2HRH3 | |
| SCHEMBL28374092 | 0.78 | — | — | |
| SCHEMBL27573102 | 0.75 | GNAI3 (0.55) | — | |
| SCHEMBL27573106 | 0.75 | GNAI3 (0.55) | — | |
| SCHEMBL27573100 | 0.75 | GNAI3 (0.55) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1235831-A2 | NEW OXABISPIDINE COMPOUNDS USEFUL IN THE TREATMENT OF CARDIAC ARRHYTHMIAS | AstraZeneca AB (SE) | 2002-09-04 | — | — | EP | disclosed |
| WO-2001028992-A2 | NEW OXABISPIDINE COMPOUNDS USEFUL IN THE TREATMENT OF CARDIAC ARRHYTHMIAS | ASTRAZENECA AB (SE) | 2001-04-26 | — | — | WO | disclosed |