Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 3/20 | 0.60 |
| ▸ | MMP9 | P14780 | 2/20 | 0.60 |
| ▸ | MMP8 | P22894 | 2/20 | 0.60 |
| ▸ | CTSL | P07711 | 1/20 | 0.55 |
| ▸ | CTSS | P25774 | 1/20 | 0.55 |
| ▸ | CTSK | P43235 | 1/20 | 0.55 |
| ▸ | TACR1 | P25103 | 1/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.47 |
| ▸ | GHSR | Q92847 | 2/20 | 0.47 |
| ▸ | F10 | P00742 | 2/20 | 0.44 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.41 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.41 |
| ▸ | KLK1 | P06870 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL760987 | 0.88 | F10 (0.55) | MMP2MMP9MMP8CTSLCTSS | |
| SCHEMBL14615508 | 0.88 | CTSL (0.52) | MMP2MMP9MMP8CTSLCTSS | |
| SCHEMBL14615468 | 0.87 | CTSL (0.56) | MMP2MMP9MMP8CTSLCTSS | |
| SCHEMBL14615606 | 0.86 | CTSL (0.56) | MMP2MMP9MMP8CTSLCTSS | |
| SCHEMBL14615501 | 0.86 | CTSL (0.56) | MMP2MMP9MMP8CTSLCTSS | |
| SCHEMBL737818 | 0.86 | GHSR (0.52) | MMP2MMP9MMP8CTSLCTSS | |
| SCHEMBL762231 | 0.85 | CTSL (0.49) | MMP2MMP9MMP8CTSLCTSS | |
| SCHEMBL5556628 | 0.84 | CTSS (0.76) | MMP2MMP9MMP8CTSLCTSS | |
| SCHEMBL737099 | 0.84 | GHSR (0.68) | MMP2MMP9MMP8CTSLCTSS | |
| SCHEMBL14615585 | 0.84 | CTSL (0.54) | MMP2MMP9MMP8CTSLCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8138218-B2 | Growth hormone secretagogues | IPSEN PHARMA S.A.S. (FR) | 2012-03-20 | — | — | US | disclosed |
| US-20090131478-A1 | Growth Hormone Secretagogues | IPSEN PHARMA S.A.S. (FR) | 2009-05-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090131478-A1 | Growth Hormone Secretagogues | GHSR, GHRHR, GHITM | MMP2 1089/4885MMP9 3107/4885MMP8 3196/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.