SCHEMBL7610482

SCHEMBL7610482

CCOC(=O)N(CC(=O)O)c1ccc(F)cc1

nearest known ligand 0.54

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.46
MAPT P10636 2/20 0.42
LMNA P02545 2/20 0.42
MEN1 O00255 1/20 0.42
CYP1A2 P05177 1/20 0.42
CYP2C9 P11712 1/20 0.42
CYP2C19 P33261 1/20 0.42
KMT2A Q03164 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
CTDSP1 Q9GZU7 1/20 0.41
TDP1 Q9NUW8 2/20 0.41
PTGIR P43119 2/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
KDM4E B2RXH2 1/20 0.40
GAA P10253 1/20 0.40
LTB4R2 Q9NPC1 1/20 0.40
PTGDR Q13258 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10779414 0.86 CA12 (0.46) TSHRLMNAMEN1KMT2ACTDSP1
SCHEMBL1203729 0.85 SMN1; SMN2 (0.54) TSHRMAPTLMNAMEN1CYP1A2
SCHEMBL204330 0.84 MLYCD (0.40)
SCHEMBL5967396 0.81 KEAP1 (0.47) MAPTKMT2ATDP1
SCHEMBL3349318 0.80 MLYCD (0.41) MEN1KMT2ALTB4R2
SCHEMBL8132818 0.80 ALDH1A1 (0.52) MAPTLMNAMEN1KMT2ASMN1; SMN2
SCHEMBL14248561 0.78 ACHE (0.44) MEN1KMT2AKDM4E
SCHEMBL8165909 0.78 FABP7 (0.45) MAPTLMNAKDM4E
SCHEMBL27489900 0.76 PTGIR (0.55) MAPTMEN1CYP1A2CYP2C9CYP2C19
SCHEMBL14248928 0.75 TDP1 (0.51) TSHRMAPTLMNAMEN1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6432980-B1 PREVENTION OF COCCIDIOSIS IN POULTRY MERCK & CO., INC. 2002-08-13 US disclosed