Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 16/20 | 0.40 |
| ▸ | PDCD1 | Q15116 | 8/20 | 0.40 |
| ▸ | CFD | P00746 | 1/20 | 0.35 |
| ▸ | TPSB2 | P20231 | 1/20 | 0.35 |
| ▸ | VDR | P11473 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7606748 | 0.89 | VDR (0.35) | CD274PDCD1CFDTPSB2VDR | |
| SCHEMBL7613344 | 0.88 | RXRA (0.34) | CD274PDCD1CFDTPSB2VDR | |
| SCHEMBL7604546 | 0.84 | CD274 (0.40) | CD274PDCD1VDR | |
| SCHEMBL7612427 | 0.82 | CD274 (0.40) | CD274PDCD1 | |
| SCHEMBL7606363 | 0.81 | VDR (0.43) | VDR | |
| SCHEMBL7610926 | 0.80 | VDR (0.42) | VDR | |
| SCHEMBL7610503 | 0.78 | VDR (0.42) | VDR | |
| SCHEMBL6564914 | 0.78 | VDR (0.50) | CD274PDCD1VDRMAPTMAPK1 | |
| SCHEMBL7610502 | 0.77 | VDR (0.42) | VDR | |
| SCHEMBL7608523 | 0.75 | VDR (0.41) | VDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1235777-A2 | VITAMIN D ANALOGUES | Galderma Research & Development, S.N.C. (FR) | 2002-09-04 | — | — | EP | claimed |
| WO-2001038303-A2 | VITAMIN D ANALOGUES | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2001-05-31 | — | — | WO | claimed |
| EP-1235777-A2 | VITAMIN D ANALOGUES | Galderma Research & Development, S.N.C. (FR) | 2002-09-04 | — | — | EP | disclosed |
| WO-2001038303-A2 | VITAMIN D ANALOGUES | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2001-05-31 | — | — | WO | disclosed |