Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 10/20 | 0.40 |
| ▸ | PDCD1 | Q15116 | 3/20 | 0.40 |
| ▸ | VDR | P11473 | 2/20 | 0.34 |
| ▸ | PTGES | O14684 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7612422 | 0.84 | CD274 (0.40) | CD274PDCD1VDR | |
| SCHEMBL7612427 | 0.82 | CD274 (0.40) | CD274PDCD1 | |
| SCHEMBL6564914 | 0.78 | VDR (0.50) | CD274PDCD1VDR | |
| SCHEMBL7611585 | 0.77 | VDR (0.42) | VDRALOX5 | |
| SCHEMBL7606742 | 0.76 | VDR (0.35) | CD274PDCD1VDR | |
| SCHEMBL7606748 | 0.75 | VDR (0.35) | CD274PDCD1VDR | |
| SCHEMBL7606753 | 0.74 | VDR (0.35) | CD274PDCD1VDR | |
| SCHEMBL7613344 | 0.74 | RXRA (0.34) | CD274PDCD1VDR | |
| SCHEMBL7608281 | 0.73 | FFAR1 (0.43) | — | |
| SCHEMBL6563045 | 0.71 | VDR (0.47) | CD274PDCD1VDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1235777-A2 | VITAMIN D ANALOGUES | Galderma Research & Development, S.N.C. (FR) | 2002-09-04 | — | — | EP | disclosed |
| WO-2001038303-A2 | VITAMIN D ANALOGUES | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2001-05-31 | — | — | WO | disclosed |