Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.48 |
| ▸ | TSHR | P16473 | 4/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | ELANE | P08246 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13319273 | 0.82 | MEN1 (0.56) | KDM4ENPSR1ALDH1A1TSHRL3MBTL1 | |
| SCHEMBL7610887 | 0.78 | POLB (0.47) | KDM4ENPSR1ALDH1A1TSHRL3MBTL1 | |
| SCHEMBL14588671 | 0.77 | LMNA (0.60) | KDM4EALDH1A1L3MBTL1POLBMEN1 | |
| SCHEMBL14588669 | 0.75 | KMT2A (0.50) | KDM4ENPSR1ALDH1A1TSHRL3MBTL1 | |
| SCHEMBL7606717 | 0.75 | KDM4E (0.58) | KDM4ENPSR1ALDH1A1TSHRCYP1A2 | |
| SCHEMBL14588660 | 0.74 | ALDH1A1 (0.56) | KDM4ENPSR1ALDH1A1TSHRL3MBTL1 | |
| SCHEMBL14588661 | 0.74 | CYP1A2 (0.66) | KDM4ENPSR1ALDH1A1TSHRL3MBTL1 | |
| SCHEMBL14588665 | 0.74 | CYP1A2 (0.62) | KDM4ENPSR1ALDH1A1TSHRCYP1A2 | |
| SCHEMBL860065 | 0.74 | ALDH1A1 (0.56) | KDM4ENPSR1ALDH1A1TSHRL3MBTL1 | |
| SCHEMBL8995752 | 0.73 | PNP (0.41) | KDM4EALDH1A1TSHRCYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020082268-A1 | Therapeutic compounds for the treatment of asthma and allergy, and methods of use thereof | SEPRACOR INC. | 2002-06-27 | — | — | US | disclosed |
| WO-2001070737-A2 | THERAPEUTIC HETEROCYCLIC COMPOUNDS FOR THE TREATMENT OF ASTHMA AND ALLERGY AND USE THEREOF | SEPRACOR, INC. (US) | 2001-09-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020082268-A1 | Therapeutic compounds for the treatment of asthma and allergy, and methods of use thereof | LTC4S, LTA4H, HRH2 | KDM4E 3028/4885NPSR1 1658/4885ALDH1A1 417/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.