Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 3/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | HTR1F | P30939 | 1/20 | 0.39 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.39 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.39 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.39 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.39 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7341097 | 0.81 | KDM4E (0.50) | NPC1ALDH1A1RAB9ABACE1BACE2 | |
| SCHEMBL6419679 | 0.79 | ANO1 (0.47) | NPC1ALDH1A1GAARAB9ASMN1; SMN2 | |
| SCHEMBL29503927 | 0.79 | ANO1 (0.47) | NPC1ALDH1A1GAARAB9ASMN1; SMN2 | |
| SCHEMBL12579446 | 0.78 | TRPA1 (0.44) | NPC1ALDH1A1GAARAB9ASMN1; SMN2 | |
| SCHEMBL108305 | 0.76 | P2RX7 (0.50) | NPC1ALDH1A1GAARAB9ASMN1; SMN2 | |
| SCHEMBL428478 | 0.76 | NPC1 (0.49) | NPC1ALDH1A1GAARAB9ASMN1; SMN2 | |
| SCHEMBL31723056 | 0.76 | GABRG2 (0.57) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL19249270 | 0.76 | GRM5 (0.55) | NPC1ALDH1A1GAARAB9ASMN1; SMN2 | |
| SCHEMBL6417995 | 0.74 | CNR2 (0.61) | — | |
| SCHEMBL424744 | 0.73 | MAPK1 (0.65) | NPC1ALDH1A1GAARAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6384033-B1 | DRUGS FOR VISION DEFECTS | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2002-05-07 | — | — | US | disclosed |