Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | ANPEP | P15144 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7864103 | 0.88 | CYP3A4 (0.43) | SMN1; SMN2CYP2C9CYP3A4CYP2C19LMNA | |
| SCHEMBL7614012 | 0.82 | CYP3A4 (0.40) | SMN1; SMN2CYP2C9ANPEPCYP3A4CYP2C19 | |
| SCHEMBL7614988 | 0.82 | CYP3A4 (0.40) | SMN1; SMN2CYP2C9ANPEPCYP3A4CYP2C19 | |
| SCHEMBL7613269 | 0.82 | CYP3A4 (0.40) | SMN1; SMN2CYP2C9ANPEPCYP3A4CYP2C19 | |
| SCHEMBL7611749 | 0.82 | CYP3A4 (0.40) | SMN1; SMN2CYP2C9ANPEPCYP3A4CYP2C19 | |
| SCHEMBL7619724 | 0.82 | CYP3A4 (0.40) | SMN1; SMN2CYP2C9ANPEPCYP3A4CYP2C19 | |
| SCHEMBL5498263 | 0.79 | ATM (0.34) | L3MBTL1ATMCTSLCTSKSMN1; SMN2 | |
| SCHEMBL5491867 | 0.79 | ATM (0.34) | L3MBTL1ATMCTSLCTSKSMN1; SMN2 | |
| SCHEMBL7862909 | 0.76 | PPID (0.43) | L3MBTL1ATMSMN1; SMN2CYP2C9CYP2D6 | |
| SCHEMBL7957020 | 0.72 | OPRM1 (0.38) | SMN1; SMN2ANPEPMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0829473-B1 | PROCESSES FOR PREPARING CYCLIC COMPOUNDS | DAIICHI SEIYAKU CO (JP) | 2002-08-07 | — | — | EP | disclosed |
| EP-1148047-A2 | Processes for preparing cyclic compounds | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2001-10-24 | — | — | EP | disclosed |
| US-6218548-B1 | (TRIARYLMETHYL)AMINOSPIROPYRROLES | DAIICHI PAHARMACEUTICAL CO., LTD. (JP) | 2001-04-17 | — | — | US | disclosed |
| US-6013806-A | ANTIBACTEIRAL | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2000-01-11 | — | — | US | disclosed |
| EP-0829473-A1 | PROCESSES FOR PREPARING CYCLIC COMPOUNDS | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1998-03-18 | — | — | EP | disclosed |