Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | ANPEP | P15144 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.38 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7614988 | 1.00 | CYP3A4 (0.40) | CYP3A4CYP2C19KCNA3OPRM1SMN1; SMN2 | |
| SCHEMBL7611749 | 1.00 | CYP3A4 (0.40) | CYP3A4CYP2C19KCNA3OPRM1SMN1; SMN2 | |
| SCHEMBL7619724 | 1.00 | CYP3A4 (0.40) | CYP3A4CYP2C19KCNA3OPRM1SMN1; SMN2 | |
| SCHEMBL7613269 | 1.00 | CYP3A4 (0.40) | CYP3A4CYP2C19KCNA3OPRM1SMN1; SMN2 | |
| SCHEMBL7864103 | 0.88 | CYP3A4 (0.43) | CYP3A4CYP2C19KCNA3OPRM1SMN1; SMN2 | |
| SCHEMBL7957020 | 0.84 | OPRM1 (0.38) | KCNA3OPRM1SMN1; SMN2ANPEPOPRD1 | |
| SCHEMBL7612508 | 0.82 | LTC4S (0.43) | ALDH1A1MEN1KMT2APOLB | |
| SCHEMBL7614073 | 0.82 | L3MBTL1 (0.42) | CYP3A4CYP2C19KCNA3SMN1; SMN2ANPEP | |
| SCHEMBL7862909 | 0.80 | PPID (0.43) | CYP3A4CYP2C19KCNA3OPRM1SMN1; SMN2 | |
| SCHEMBL5682210 | 0.75 | KCNA3 (0.49) | CYP3A4CYP2C19KCNA3OPRM1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0829473-B1 | PROCESSES FOR PREPARING CYCLIC COMPOUNDS | DAIICHI SEIYAKU CO (JP) | 2002-08-07 | — | — | EP | disclosed |
| EP-1148047-A2 | Processes for preparing cyclic compounds | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2001-10-24 | — | — | EP | disclosed |
| US-6218548-B1 | (TRIARYLMETHYL)AMINOSPIROPYRROLES | DAIICHI PAHARMACEUTICAL CO., LTD. (JP) | 2001-04-17 | — | — | US | disclosed |
| US-6013806-A | ANTIBACTEIRAL | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2000-01-11 | — | — | US | disclosed |
| EP-0829473-A1 | PROCESSES FOR PREPARING CYCLIC COMPOUNDS | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1998-03-18 | — | — | EP | disclosed |