SCHEMBL761410

SCHEMBL761410

CS(=O)(=O)OC1CC2CCC(C1)N2c1ccc(C(F)(F)F)cn1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR119 Q8TDV5 1/20 0.46
GAA P10253 1/20 0.45
HCRTR1 O43613 2/20 0.41
HCRTR2 O43614 2/20 0.41
KDM4E B2RXH2 3/20 0.41
ABL1 P00519 1/20 0.41
LMNA P02545 1/20 0.41
NAAA Q02083 1/20 0.41
CXCR3 P49682 5/20 0.40
HRH3 Q9Y5N1 3/20 0.40
SMN1; SMN2 Q16637 3/20 0.40
ALDH1A1 P00352 2/20 0.40
MAPT P10636 2/20 0.40
APAF1 O14727 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
HPGD P15428 1/20 0.39
SMO Q99835 1/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12371191 1.00 GPR119 (0.46) GPR119GAAHCRTR1HCRTR2KDM4E
SCHEMBL15827400 1.00 GPR119 (0.46) GPR119GAAHCRTR1HCRTR2KDM4E
SCHEMBL13813126 0.81 HRH3 (0.47) HCRTR1HCRTR2KDM4EABL1LMNA
SCHEMBL384506 0.81 HRH3 (0.47) HCRTR1HCRTR2KDM4EABL1LMNA
SCHEMBL13799808 0.81 HRH3 (0.47) HCRTR1HCRTR2KDM4EABL1LMNA
SCHEMBL10107231 0.81 HRH3 (0.47) HCRTR1HCRTR2KDM4EABL1LMNA
SCHEMBL757363 0.81 GPR119 (0.61) GPR119GAAKDM4EABL1LMNA
SCHEMBL16433630 0.79 KDM4E (0.45) GPR119GAAHCRTR1HCRTR2KDM4E
SCHEMBL10107100 0.79 KDM4E (0.48) GPR119KDM4EABL1LMNACXCR3
SCHEMBL10107239 0.79 KDM4E (0.48) GPR119KDM4EABL1LMNACXCR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2050745-B1 N-PYRIDYLPIPERIDINE COMPOUND, METHOD FOR PRODUCING THE SAME, AND PEST CONTROL AGENT OTSUKA AGRITECHNO CO LTD (JP) 2012-03-21 EP disclosed
US-20100137582-A1 N-PYRIDYLPIPERIDINE COMPOUND, METHOD FOR PRODUCING THE SAME, AND PEST CONTROL AGENT OTSUKA CHEMICAL CO., LTD. (JP) 2010-06-03 US disclosed
EP-2050745-A1 N-PYRIDYLPIPERIDINE COMPOUND, METHOD FOR PRODUCING THE SAME, AND PEST CONTROL AGENT Otsuka Chemical Co., Ltd. (JP) 2009-04-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100137582-A1 N-PYRIDYLPIPERIDINE COMPOUND, METHOD FOR PRODUCING THE SAME, AND PEST CONTROL AGENT HRH4, NOX4, PRDX4 GPR119 3349/4885GAA 4316/4885HCRTR1 329/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.