Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | BMP1 | P13497 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | CCR5 | P51681 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4382398 | 0.83 | POLB (0.52) | POLBTSHRSMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL1406138 | 0.81 | ALDH1A1 (0.42) | TSHRSMN1; SMN2ALDH1A1L3MBTL1TDP1 | |
| SCHEMBL7479624 | 0.76 | SMN1; SMN2 (0.49) | POLBTSHRSMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL396520 | 0.75 | PTGS1 (0.46) | POLBTSHRALDH1A1L3MBTL1BMP1 | |
| SCHEMBL9680690 | 0.73 | THRB (0.44) | ALDH1A1MAPT | |
| SCHEMBL27987587 | 0.73 | TAAR1 (0.55) | POLBTSHRSMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL28325136 | 0.73 | NPC1 (0.51) | POLBTSHRSMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL28324038 | 0.73 | NPC1 (0.51) | POLBTSHRSMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL28325134 | 0.73 | NPC1 (0.51) | POLBTSHRSMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL28324055 | 0.73 | NPC1 (0.51) | POLBTSHRSMN1; SMN2ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0766658-B1 | PROCESS FOR IMPROVING ENANTIOMERIC PURITY OF ALDEHYDES | UNION CARBIDE CHEM PLASTIC (US) | 2002-04-10 | — | — | EP | claimed |
| EP-0862549-B1 | PROCESS FOR PREPARING OPTICALLY ACTIVE CARBOXYLIC ACIDS | UNION CARBIDE CHEM PLASTIC (US) | 2000-05-31 | — | — | EP | claimed |
| EP-0600020-B1 | ASYMMETRIC SYNTHESES | UNION CARBIDE CHEM PLASTIC (US) | 1996-01-31 | — | — | EP | claimed |