SCHEMBL761574

SCHEMBL761574

NC(=O)[C@@H](Cc1ccc2ccccc2c1)NC(=O)C1(N)CCNCC1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FCER2 P06734 4/20 0.50
MC1R Q01726 3/20 0.47
MC5R P33032 2/20 0.47
GHSR Q92847 2/20 0.43
SLC6A4 P31645 2/20 0.43
MMP9 P14780 2/20 0.42
MMP3 P08254 1/20 0.42
MMP8 P22894 1/20 0.42
CA2 P00918 1/20 0.42
MME P08473 2/20 0.42
ACE P12821 2/20 0.42
CPA1 P15085 2/20 0.42
ACE2 Q9BYF1 2/20 0.42
MC4R P32245 1/20 0.41
MC3R P41968 1/20 0.41
ALB P02768 1/20 0.41
IL2 P60568 1/20 0.41
SLC6A2 P23975 1/20 0.41
SLC6A3 Q01959 1/20 0.41
IDE P14735 3/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL762500 0.81 GHSR (0.52) GHSRSLC6A4MMP9MMP8MME
SCHEMBL10054043 0.81 CAPN1 (0.57) FCER2MC1RMC5RSLC6A4MMP9
SCHEMBL14615484 0.77 GHSR (0.51) FCER2MC1RMC5RGHSRMMP9
SCHEMBL6469894 0.76 TACR1 (0.62) FCER2MC1RMC5RMMP9MMP3
SCHEMBL14615504 0.76 SLC6A4 (0.45) SLC6A4SLC6A2SLC6A3
SCHEMBL738034 0.75 GHSR (0.60) MC1RMC5RGHSRMMP9MMP8
SCHEMBL761452 0.75 GHSR (0.73) MC1RMC5RGHSRACE
SCHEMBL14527547 0.75 CAPN1 (0.58) FCER2MC1RMMP9MMP3MC4R
SCHEMBL30995920 0.74 FCER2 (0.63) FCER2MC1RMC5RMMP9MMP3
SCHEMBL761165 0.74 F10 (0.52) GHSRMMP9MMP8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8138218-B2 Growth hormone secretagogues IPSEN PHARMA S.A.S. (FR) 2012-03-20 US disclosed
US-20090131478-A1 Growth Hormone Secretagogues IPSEN PHARMA S.A.S. (FR) 2009-05-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090131478-A1 Growth Hormone Secretagogues GHSR, GHRHR, GHITM FCER2 4722/4885MC1R 68/4885MC5R 168/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.