Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 5/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11470650 | 1.00 | ALDH1A1 (0.42) | ALDH1A1PKMHPGDGPR84KCNH2 | |
| SCHEMBL449372 | 1.00 | ALDH1A1 (0.42) | ALDH1A1PKMHPGDGPR84KCNH2 | |
| SCHEMBL7614190 | 0.79 | HRH3 (0.31) | — | |
| SCHEMBL7618344 | 0.78 | HRH4 (0.45) | ALDH1A1KCNH2 | |
| SCHEMBL7625860 | 0.77 | CNR1 (0.43) | ALDH1A1HPGD | |
| SCHEMBL7622787 | 0.77 | HRH3 (0.33) | — | |
| SCHEMBL7614088 | 0.77 | TBXAS1 (0.61) | — | |
| SCHEMBL7621773 | 0.77 | TBXAS1 (0.61) | — | |
| SCHEMBL7625592 | 0.77 | TBXAS1 (0.45) | — | |
| SCHEMBL7616317 | 0.76 | HRH3 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1232166-A2 | SYNTHESIS OF 2'-DEOXY-L-NUCLEOSIDES | Pharmasset Limited (US) | 2002-08-21 | — | — | EP | disclosed |
| WO-2001034618-A2 | SYNTHESIS OF 2'-DEOXY-L-NUCLEOSIDES | PHARMASSET LIMITED (US) | 2001-05-17 | — | — | WO | disclosed |