Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
| ▸ | PIK3R2 | O00459 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8476032 | 0.91 | CNR2 (0.52) | CNR2ALDH1A1KDM4EHSD17B10POLB | |
| SCHEMBL8474630 | 0.90 | KMT2A (0.42) | CNR2ALDH1A1HSD17B10MAPTMEN1 | |
| SCHEMBL7615399 | 0.89 | CNR2 (0.39) | CNR2ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL7617024 | 0.87 | ALDH1A1 (0.38) | CNR2ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL8472353 | 0.86 | ALDH1A1 (0.45) | ALDH1A1KDM4EHPGDHSD17B10MAPK1 | |
| SCHEMBL7615030 | 0.85 | KMT2A (0.39) | CNR2ALDH1A1MAPK1MAPTMEN1 | |
| SCHEMBL8477092 | 0.85 | DRD2 (0.44) | CNR2MAPK1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL7615408 | 0.85 | CNR2 (0.36) | CNR2ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL9079757 | 0.84 | CNR2 (0.49) | CNR2ALDH1A1HPGDMAPTSMN1; SMN2 | |
| SCHEMBL8477366 | 0.84 | ALDH1A1 (0.47) | CNR2ALDH1A1KDM4EPOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5891902-A | OSTEOPOROSIS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1999-04-06 | — | — | US | disclosed |
| EP-0782989-A1 | INDOLE DERIVATIVES | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1997-07-09 | — | — | EP | disclosed |