Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 3/20 | 0.38 |
| ▸ | CTSK | P43235 | 3/20 | 0.38 |
| ▸ | CTSL | P07711 | 2/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | MMP14 | P50281 | 1/20 | 0.37 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5640387 | 0.81 | LMNA (0.46) | ALDH1A1LMNATSHRHSD17B10POLB | |
| SCHEMBL3368388 | 0.78 | AOC3 (0.42) | ALDH1A1LMNATSHRHSD17B10HRH1 | |
| SCHEMBL4574134 | 0.77 | RIPK1 (0.46) | MAPK1 | |
| SCHEMBL16935664 | 0.77 | TAAR1 (0.46) | MAPK1HRH1SLC6A3TAAR1 | |
| SCHEMBL28866374 | 0.77 | SMN1; SMN2 (0.36) | ALDH1A1LMNACYP3A4ALOX15TSHR | |
| SCHEMBL13996016 | 0.76 | ALDH1A1 (0.54) | ALDH1A1LMNACYP3A4ALOX15TSHR | |
| SCHEMBL19368275 | 0.76 | ALDH1A1 (0.54) | ALDH1A1LMNACYP3A4ALOX15TSHR | |
| SCHEMBL3449545 | 0.76 | HTT (0.51) | ALDH1A1CYP3A4 | |
| SCHEMBL8701351 | 0.75 | POLB (0.45) | ALDH1A1MMEPOLB | |
| SCHEMBL24191865 | 0.75 | ALDH1A1 (0.53) | ALDH1A1LMNACYP3A4ALOX15TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0826681-B1 | EPOXYSUCCINIC ACID DERIVATIVES | NIPPON CHEMIPHAR CO (JP) | 2002-10-09 | — | — | EP | disclosed |
| US-5843992-A | Epoxysuccinic acid derivatives | NIPPON CHEMIPHAR CO., LTD. (JP) | 1998-12-01 | — | — | US | disclosed |
| EP-0826681-A1 | EPOXYSUCCINIC ACID DERIVATIVES | NIPPON CHEMIPHAR CO., LTD. (JP) | 1998-03-04 | — | — | EP | disclosed |