Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.55 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.55 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.48 |
| ▸ | MMP9 | P14780 | 1/20 | 0.48 |
| ▸ | AANAT | Q16613 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7641916 | 0.86 | MEN1 (0.58) | PDPK1RPS6KB1PTGS2MEN1KMT2A | |
| SCHEMBL7620295 | 0.81 | MEN1 (0.57) | PDPK1RPS6KB1PTGS2MEN1KMT2A | |
| SCHEMBL7617019 | 0.79 | PTGS1 (0.54) | PTGS2MEN1KMT2ASIRT1NPC1 | |
| SCHEMBL7621047 | 0.78 | MEN1 (0.53) | PTGS2MEN1KMT2ASIRT1NPC1 | |
| SCHEMBL7619256 | 0.78 | MEN1 (0.48) | PDPK1RPS6KB1PTGS2MEN1KMT2A | |
| SCHEMBL7612256 | 0.77 | MEN1 (0.47) | PDPK1RPS6KB1PTGS2MEN1KMT2A | |
| SCHEMBL7614707 | 0.74 | GFER (0.53) | MEN1KMT2ASIRT1NPC1RAB9A | |
| SCHEMBL7618887 | 0.73 | MEN1 (0.48) | PTGS2MEN1KMT2ASIRT1NPC1 | |
| SCHEMBL627038 | 0.73 | MEN1 (0.74) | MEN1KMT2ASIRT1NPC1RAB9A | |
| SCHEMBL7618839 | 0.72 | MTNR1A (0.54) | PTGS2MEN1KMT2ASIRT1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020091090-A1 | Somatostatin antagonists and agonists | COLE BRIDGET M (US) | 2002-07-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020091090-A1 | Somatostatin antagonists and agonists | GHSR, GHRHR, SSTR3 | PDPK1 3573/4885RPS6KB1 2265/4885PTGS2 4399/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.