SCHEMBL7621047

SCHEMBL7621047

NC(=O)c1c(C[CH]C(=O)NCCc2c[nH]c3ccccc23)ccc2ccccc12

nearest known ligand 0.53

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 7/20 0.53
KMT2A Q03164 7/20 0.53
LMNA P02545 2/20 0.53
SIRT1 Q96EB6 2/20 0.53
MAPT P10636 2/20 0.53
PTGS1 P23219 2/20 0.53
PTGS2 P35354 1/20 0.53
CYP1A2 P05177 1/20 0.52
PKM P14618 1/20 0.52
TSHR P16473 1/20 0.52
CYP2C19 P33261 1/20 0.52
BLM P54132 1/20 0.52
MMP9 P14780 1/20 0.50
AANAT Q16613 1/20 0.50
NPC1 O15118 1/20 0.50
RAB9A P51151 1/20 0.50
CTSC P53634 1/20 0.49
ALDH1A1 P00352 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7617019 0.85 PTGS1 (0.54) MEN1KMT2ALMNASIRT1MAPT
SCHEMBL7641916 0.83 MEN1 (0.58) MEN1KMT2ALMNASIRT1PTGS1
SCHEMBL630447 0.80 MAPT (0.47) MEN1KMT2ALMNASIRT1MAPT
SCHEMBL7618657 0.78 PDPK1 (0.55) MEN1KMT2ALMNASIRT1PTGS1
SCHEMBL7614707 0.78 GFER (0.53) MEN1KMT2ALMNASIRT1CYP1A2
SCHEMBL7618887 0.77 MEN1 (0.48) MEN1KMT2ALMNASIRT1MAPT
SCHEMBL28643186 0.76 MEN1 (0.62) MEN1KMT2ALMNASIRT1MAPT
SCHEMBL7618839 0.76 MTNR1A (0.54) MEN1KMT2ALMNASIRT1PTGS1
SCHEMBL7620295 0.76 MEN1 (0.57) MEN1KMT2ALMNASIRT1PTGS1
SCHEMBL7619256 0.75 MEN1 (0.48) MEN1KMT2ALMNASIRT1PTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020091090-A1 Somatostatin antagonists and agonists COLE BRIDGET M (US) 2002-07-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020091090-A1 Somatostatin antagonists and agonists GHSR, GHRHR, SSTR3 MEN1 882/4885KMT2A 1634/4885LMNA 2381/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.