Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP3 | P15309 | 6/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PGK1 | P00558 | 3/20 | 0.37 |
| ▸ | PGK2 | P07205 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CTSG | P08311 | 1/20 | 0.35 |
| ▸ | CMA1 | P23946 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL914870 | 0.83 | ACP3 (0.56) | ACP3SMN1; SMN2PTPN1GPR35HTR2A | |
| SCHEMBL8579622 | 0.74 | HTR2A (0.44) | GPR35HTR2AL3MBTL1POLB | |
| SCHEMBL29439367 | 0.74 | HTR2A (0.64) | GPR35HTR2AL3MBTL1POLB | |
| SCHEMBL3421056 | 0.72 | SMN1; SMN2 (0.56) | ACP3SMN1; SMN2PGK1PGK2 | |
| SCHEMBL17029074 | 0.71 | ACP3 (0.66) | ACP3SMN1; SMN2L3MBTL1PGK1PGK2 | |
| SCHEMBL916722 | 0.71 | HSD17B10 (0.61) | ACP3 | |
| SCHEMBL916426 | 0.71 | WDR5 (0.54) | ACP3GPR35POLB | |
| SCHEMBL8824574 | 0.70 | ACP3 (0.54) | ACP3SMN1; SMN2PGK1PGK2 | |
| SCHEMBL11491572 | 0.69 | ACP3 (0.62) | ACP3PTPN1PGK1PGK2 | |
| SCHEMBL578080 | 0.69 | SMN1; SMN2 (0.57) | ACP3SMN1; SMN2PGK1PGK2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1212416-A2 | NUCLEIC ACID BASED MODULATORS OF GENE EXPRESSION | RIBOZYME PHARMACEUTICALS, INC. (US) | 2002-06-12 | — | — | EP | disclosed |
| WO-2001016312-A2 | NUCLEIC ACID BASED MODULATORS OF GENE EXPRESSION | RIBOZYME PHARMACEUTICALS, INC. (US) | 2001-03-08 | — | — | WO | disclosed |