Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.50 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | DAO | P14920 | 1/20 | 0.42 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.42 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.42 |
| ▸ | HPGDS | O60760 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.39 |
| ▸ | MET | P08581 | 1/20 | 0.39 |
| ▸ | BCL2 | P10415 | 1/20 | 0.38 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL794787 | 0.69 | TAAR1 (0.44) | TAAR1CALM1GAADAONR1H2 | |
| SCHEMBL9243 | 0.67 | TAAR1 (1.00) | TAAR1CALM1GAAKMT2A | |
| SCHEMBL9305710 | 0.67 | HDAC3 (0.54) | TAAR1CALM1GAADAONR1H2 | |
| Bromide SCHEMBL29135558 | 0.65 | TAAR1 (0.96) | TAAR1CALM1GAAKMT2A | |
| SCHEMBL795316 | 0.65 | NR1H2 (0.44) | TAAR1CALM1GAADAONR1H2 | |
| SCHEMBL405100 | 0.65 | TAAR1 (0.48) | TAAR1CALM1GAADAONR1H2 | |
| SCHEMBL4494347 | 0.65 | HPGDS (0.54) | TAAR1CALM1GAADAONR1H2 | |
| SCHEMBL24317085 | 0.65 | GAA (0.50) | TAAR1CALM1GAADAONR1H2 | |
| SCHEMBL1504796 | 0.65 | MTOR (0.43) | GAANR1H2NR1H3HPGDSKMT2A | |
| SCHEMBL2697397 | 0.65 | CALM1 (0.48) | TAAR1CALM1KMT2AAOC3BCL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1232166-A2 | SYNTHESIS OF 2'-DEOXY-L-NUCLEOSIDES | Pharmasset Limited (US) | 2002-08-21 | — | — | EP | disclosed |
| WO-2001034618-A2 | SYNTHESIS OF 2'-DEOXY-L-NUCLEOSIDES | PHARMASSET LIMITED (US) | 2001-05-17 | — | — | WO | disclosed |