Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 3/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 2/20 | 0.40 |
| ▸ | MPO | P05164 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 3/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | CCNC | P24863 | 1/20 | 0.36 |
| ▸ | CDK8 | P49336 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7620401 | 0.82 | TAAR1 (0.44) | DAOTAAR1IDO1MPO | |
| SCHEMBL405100 | 0.80 | TAAR1 (0.48) | DAOTAAR1LMNA | |
| SCHEMBL29459538 | 0.73 | TAAR1 (0.60) | DAOTAAR1IDO1LTA4HMAOB | |
| SCHEMBL1263547 | 0.73 | TAAR1 (0.60) | DAOTAAR1IDO1LTA4HMAOB | |
| SCHEMBL30000562 | 0.73 | TAAR1 (0.60) | DAOTAAR1IDO1LTA4HMAOB | |
| SCHEMBL10719843 | 0.71 | TAAR1 (0.66) | DAOTAAR1IDO1HTR2CHTR2B | |
| SCHEMBL7626665 | 0.70 | TAAR1 (0.37) | DAOTAAR1IDO1LMNA | |
| SCHEMBL7616832 | 0.70 | MAPT (0.39) | DAOTAAR1IDO1LMNA | |
| SCHEMBL7615355 | 0.70 | CALM1 (0.37) | DAO | |
| SCHEMBL8093804 | 0.69 | TAAR1 (0.56) | DAOTAAR1IDO1LTA4HMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1232166-A2 | SYNTHESIS OF 2'-DEOXY-L-NUCLEOSIDES | Pharmasset Limited (US) | 2002-08-21 | — | — | EP | disclosed |
| WO-2001034618-A2 | SYNTHESIS OF 2'-DEOXY-L-NUCLEOSIDES | PHARMASSET LIMITED (US) | 2001-05-17 | — | — | WO | disclosed |