Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALM1 | P0DP23 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | NOS1 | P29475 | 1/20 | 0.36 |
| ▸ | DHFR | P00374 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7621725 | 0.83 | LTA4H (0.46) | ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL5252553 | 0.71 | ALDH1A1 (0.65) | CALM1ALDH1A1CYP19A1TSHRMAPK1 | |
| SCHEMBL2094695 | 0.70 | ALDH1A1 (0.45) | ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL405100 | 0.69 | TAAR1 (0.48) | CALM1TSHRMEN1KMT2ADAO | |
| SCHEMBL7620401 | 0.66 | TAAR1 (0.44) | MAPK1DAOCHRM2 | |
| SCHEMBL681502 | 0.64 | ALDH1A1 (0.53) | CALM1ALDH1A1NOS1CYP19A1TSHR | |
| SCHEMBL19352719 | 0.63 | CALM1 (0.56) | CALM1ALDH1A1CYP19A1MAPK1AKR1B1 | |
| SCHEMBL27657180 | 0.63 | FGFR1 (0.55) | CALM1FGFR1KDRNOS1MAPK1 | |
| SCHEMBL5982458 | 0.62 | LPO (0.36) | ALDH1A1CYP19A1TSHRMAPK1MEN1 | |
| SCHEMBL18557216 | 0.62 | ALDH1A1 (0.44) | CALM1ALDH1A1CYP19A1TSHRDAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1232166-A2 | SYNTHESIS OF 2'-DEOXY-L-NUCLEOSIDES | Pharmasset Limited (US) | 2002-08-21 | — | — | EP | disclosed |
| WO-2001034618-A2 | SYNTHESIS OF 2'-DEOXY-L-NUCLEOSIDES | PHARMASSET LIMITED (US) | 2001-05-17 | — | — | WO | disclosed |