Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 6/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.36 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7055574 | 0.72 | CCNC (0.47) | HPGDALDH1A1HTTKDM4ERAB9A | |
| SCHEMBL7254159 | 0.68 | PIM1 (0.60) | — | |
| SCHEMBL5313993 | 0.66 | RAB9A (0.50) | ALDH1A1HTTMAPTPIK3R1PIK3CA | |
| SCHEMBL1219546 | 0.63 | CASP3 (0.61) | HPGDALDH1A1HTTMAPTLMNA | |
| SCHEMBL20804573 | 0.62 | MAPK14 (0.39) | HPGDALDH1A1MAPTLMNASMN1; SMN2 | |
| SCHEMBL7621192 | 0.61 | CDK8 (0.39) | HPGDALDH1A1HTTMAPTLMNA | |
| SCHEMBL7797446 | 0.60 | ICAM1 (0.46) | ALDH1A1KDM4ERAB9AMAPK1 | |
| SCHEMBL28304760 | 0.60 | MAOA (0.43) | HPGDALDH1A1HTTMAPTLMNA | |
| SCHEMBL11384667 | 0.60 | RAB9A (0.50) | HPGDALDH1A1HTTLMNANPSR1 | |
| SCHEMBL21535251 | 0.59 | PIK3R1 (0.58) | HPGDALDH1A1MAPTLMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1181296-A1 | CELL ADHESION-INHIBITING ANTIINFLAMMATORY COMPOUNDS | ABBOTT LABORATORIES (US) | 2002-02-27 | — | — | EP | disclosed |
| WO-2000075145-A1 | CELL ADHESION-INHIBITING ANTIINFLAMMATORY COMPOUNDS | ABBOTT LABORATORIES (US) | 2000-12-14 | — | — | WO | disclosed |