Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ICAM1 | P05362 | 1/20 | 0.46 |
| ▸ | SELE | P16581 | 1/20 | 0.46 |
| ▸ | CDK8 | P49336 | 5/20 | 0.43 |
| ▸ | MAPK8 | P45983 | 3/20 | 0.43 |
| ▸ | CDK9 | P50750 | 2/20 | 0.43 |
| ▸ | MAP2K1 | Q02750 | 2/20 | 0.43 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.43 |
| ▸ | AURKA | O14965 | 1/20 | 0.43 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.43 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.43 |
| ▸ | PAK4 | O96013 | 1/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | RET | P07949 | 1/20 | 0.43 |
| ▸ | PIM1 | P11309 | 1/20 | 0.43 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.43 |
| ▸ | PRKACA | P17612 | 1/20 | 0.43 |
| ▸ | FLT1 | P17948 | 1/20 | 0.43 |
| ▸ | LTK | P29376 | 1/20 | 0.43 |
| ▸ | GRK5 | P34947 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7855399 | 0.87 | CDK8 (0.48) | ICAM1SELECDK8MAPK8CDK9 | |
| SCHEMBL7055574 | 0.78 | CCNC (0.47) | ICAM1SELECDK8CDK9FLT1 | |
| SCHEMBL16011543 | 0.73 | CDK8 (0.50) | ICAM1SELECDK8MAPK8CDK9 | |
| SCHEMBL7056416 | 0.73 | KDR (0.41) | ICAM1SELECDK8MAP4K4PIM1 | |
| SCHEMBL8476094 | 0.72 | ALDH1A1 (0.51) | MAPK8ALDH1A1TDP1MAPK10RAB9A | |
| SCHEMBL742272 | 0.68 | RAB9A (0.75) | MAPK8ALDH1A1TDP1RAB9AROCK2 | |
| SCHEMBL8568267 | 0.68 | ALDH1A1 (0.48) | MAPK8PIM1ALDH1A1TDP1MAPK10 | |
| SCHEMBL4558531 | 0.68 | S1PR3 (0.46) | ALDH1A1TDP1RAB9APARP10KDM4E | |
| SCHEMBL4165034 | 0.67 | SLC8A1 (0.54) | ICAM1SELECDK8CCNCPARP10 | |
| Hydrochloric Acid SCHEMBL6831509 | 0.67 | RAB9A (0.73) | MAPK8ALDH1A1TDP1RAB9AROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20010020030-A1 | Cell adhesion-inhibiting antiinflammatory compounds | ABBVIE INC. | 2001-09-06 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010020030-A1 | Cell adhesion-inhibiting antiinflammatory compounds | ICAM1, VCAM1, EPCAM | ICAM1 1/4885SELE 16/4885CDK8 2986/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.