SCHEMBL7621844

SCHEMBL7621844

CCCCON=C(c1ccccc1)c1ccc(OCCCCOc2c(Cl)cc(OCC=C(Cl)Cl)cc2Cl)nc1

nearest known ligand 0.39

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
PSEN1 P49768 3/20 0.39
PSEN2 P49810 3/20 0.39
APH1B Q8WW43 3/20 0.39
NCSTN Q92542 3/20 0.39
APH1A Q96BI3 3/20 0.39
PSENEN Q9NZ42 3/20 0.39
ESR1 P03372 1/20 0.39
TBXAS1 P24557 9/20 0.36
TBXA2R P21731 11/20 0.36
PPARG P37231 2/20 0.35
PPARA Q07869 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7624607 0.99 PSEN1 (0.39) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL7624569 0.94 TBXAS1 (0.36) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL7628012 0.93 TBXAS1 (0.36) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL7621105 0.92 TBXA2R (0.34) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL7617751 0.91 TBXA2R (0.34) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL7624587 0.89 MAPT (0.32) TBXAS1TBXA2R
SCHEMBL7622724 0.89 POLB (0.34) TBXAS1TBXA2R
SCHEMBL7619887 0.89 SMN1; SMN2 (0.33) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL7618235 0.89 MAPT (0.34) PPARGPPARA
SCHEMBL7618139 0.88 POLB (0.34) TBXAS1TBXA2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6448444-B2 INSECTICIDES, MITICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-09-10 US disclosed
US-6437184-B1 INSECTICIDES, ACARICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-08-20 US disclosed
US-20020019569-A1 Oxime compounds, their use, and intermediates for their production SUMITOMO CHEMICAL COMPANY, LIMITED 2002-02-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020019569-A1 Oxime compounds, their use, and intermediates for their production CBR3, CBR1, NOX3 PSEN1 4656/4885PSEN2 4818/4885APH1B 2790/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.