SCHEMBL7628012

SCHEMBL7628012

CCON=C(c1ccccc1)c1ccc(OCCCOc2c(Cl)cc(OCC=C(Cl)Cl)cc2Cl)nc1

nearest known ligand 0.36

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TBXAS1 P24557 9/20 0.36
TBXA2R P21731 11/20 0.33
MAPT P10636 2/20 0.32
HPGD P15428 1/20 0.31
MAPK1 P28482 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
PSEN1 P49768 3/20 0.31
PSEN2 P49810 3/20 0.31
APH1B Q8WW43 3/20 0.31
NCSTN Q92542 3/20 0.31
APH1A Q96BI3 3/20 0.31
PSENEN Q9NZ42 3/20 0.31
PPARG P37231 2/20 0.31
PPARA Q07869 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7624569 0.99 TBXAS1 (0.36) TBXAS1TBXA2RMAPTPSEN1PSEN2
SCHEMBL7617751 0.95 TBXA2R (0.34) TBXAS1TBXA2RMAPTHPGDMAPK1
SCHEMBL7624607 0.94 PSEN1 (0.39) TBXAS1TBXA2RPSEN1PSEN2APH1B
SCHEMBL7621105 0.94 TBXA2R (0.34) TBXAS1TBXA2RPSEN1PSEN2APH1B
SCHEMBL7621844 0.93 PSEN1 (0.39) TBXAS1TBXA2RPSEN1PSEN2APH1B
SCHEMBL7618235 0.92 MAPT (0.34) MAPTHPGDMAPK1L3MBTL1PPARG
SCHEMBL7618139 0.91 POLB (0.34) TBXAS1TBXA2RMAPTHPGD
SCHEMBL7624587 0.91 MAPT (0.32) TBXAS1TBXA2RMAPTHPGDMAPK1
SCHEMBL7622724 0.91 POLB (0.34) TBXAS1TBXA2RMAPTHPGD
SCHEMBL7617025 0.90 MAPT (0.31) MAPTHPGDMAPK1L3MBTL1PSEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6448444-B2 INSECTICIDES, MITICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-09-10 US disclosed
US-6437184-B1 INSECTICIDES, ACARICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-08-20 US disclosed
US-20020019569-A1 Oxime compounds, their use, and intermediates for their production SUMITOMO CHEMICAL COMPANY, LIMITED 2002-02-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020019569-A1 Oxime compounds, their use, and intermediates for their production CBR3, CBR1, NOX3 TBXAS1 1565/4885TBXA2R 2665/4885MAPT 4623/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.