SCHEMBL7624587

SCHEMBL7624587

CON=C(c1ccccc1)c1ccc(OCCCCOc2c(Cl)cc(OCC=C(Cl)Cl)cc2Cl)nc1

nearest known ligand 0.32

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.32
HPGD P15428 1/20 0.32
MAPK1 P28482 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
TBXA2R P21731 2/20 0.30
TBXAS1 P24557 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7618235 0.99 MAPT (0.34) MAPTHPGDMAPK1L3MBTL1
SCHEMBL7624569 0.92 TBXAS1 (0.36) MAPTTBXA2RTBXAS1
SCHEMBL7621105 0.92 TBXA2R (0.34) TBXA2RTBXAS1
SCHEMBL7628012 0.91 TBXAS1 (0.36) MAPTHPGDMAPK1L3MBTL1TBXA2R
SCHEMBL7623039 0.91 PSEN1 (0.31)
SCHEMBL7617751 0.91 TBXA2R (0.34) MAPTHPGDMAPK1L3MBTL1TBXA2R
SCHEMBL7617025 0.90 MAPT (0.31) MAPTHPGDMAPK1L3MBTL1
SCHEMBL7622414 0.90
SCHEMBL7625484 0.89 MAPT (0.30) MAPTHPGDMAPK1L3MBTL1
SCHEMBL7621844 0.89 PSEN1 (0.39) TBXA2RTBXAS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6448444-B2 INSECTICIDES, MITICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-09-10 US disclosed
US-6437184-B1 INSECTICIDES, ACARICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-08-20 US disclosed
US-20020019569-A1 Oxime compounds, their use, and intermediates for their production SUMITOMO CHEMICAL COMPANY, LIMITED 2002-02-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020019569-A1 Oxime compounds, their use, and intermediates for their production CBR3, CBR1, NOX3 MAPT 4623/4885HPGD 881/4885MAPK1 1228/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.