Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAPDH | P04406 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 7/20 | 0.44 |
| ▸ | SLC28A2 | O43868 | 2/20 | 0.43 |
| ▸ | HSPA8 | P11142 | 2/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 6/20 | 0.43 |
| ▸ | ADORA2B | P29275 | 5/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.43 |
| ▸ | ADK | P55263 | 3/20 | 0.43 |
| ▸ | SLC29A1 | Q99808 | 2/20 | 0.43 |
| ▸ | DPP4 | P27487 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.43 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | STAT6 | P42226 | 1/20 | 0.43 |
| ▸ | PI4KA | P42356 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7617155 | 0.82 | HTR1D (0.50) | GAPDHHSD17B10ADORA3SLC28A2HSPA8 | |
| SCHEMBL846742 | 0.80 | HSPA8 (0.46) | GAPDHHSD17B10ADORA3SLC28A2HSPA8 | |
| SCHEMBL1936249 | 0.78 | ADK (0.50) | GAPDHHSD17B10ADORA3SLC28A2HSPA8 | |
| SCHEMBL15973691 | 0.78 | ADK (0.50) | GAPDHHSD17B10ADORA3SLC28A2HSPA8 | |
| SCHEMBL1666083 | 0.78 | HSPA5 (0.52) | GAPDHHSD17B10ADORA3SLC28A2HSPA8 | |
| SCHEMBL830796 | 0.78 | MAPK1 (0.50) | GAPDHHSD17B10ADORA3SLC28A2HSPA8 | |
| SCHEMBL724943 | 0.78 | MAPK1 (0.50) | GAPDHHSD17B10ADORA3SLC28A2HSPA8 | |
| SCHEMBL3841527 | 0.78 | DOT1L (0.50) | GAPDHHSD17B10ADORA3SLC28A2HSPA8 | |
| SCHEMBL830795 | 0.78 | MAPK1 (0.50) | GAPDHHSD17B10ADORA3SLC28A2HSPA8 | |
| SCHEMBL1936244 | 0.78 | ADK (0.50) | GAPDHHSD17B10ADORA3SLC28A2HSPA8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0755255-A4 | TREATMENT OF TOXOPLASMOSIS | RES CORP TECHNOLOGIES INC (US) | 2002-07-24 | — | — | EP | disclosed |
| EP-0755255-A1 | TREATMENT OF TOXOPLASMOSIS | UNIVERSITY OF ALABAMA, BIRMINGHAM RESEARCH FOUNDATION (US) | 1997-01-29 | — | — | EP | disclosed |
| WO-1996018398-A1 | TREATMENT OF TOXOPLASMOSIS | THE UNIVERSITY OF ALABAMA AT BIRMINGHAM RESEARCH FOUNDATION (US) | 1996-06-20 | — | — | WO | disclosed |