Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | BCAT1 | P54687 | 1/20 | 0.42 |
| ▸ | ACSL1 | P33121 | 2/20 | 0.41 |
| ▸ | ACSL6 | Q9UKU0 | 2/20 | 0.41 |
| ▸ | TTR | P02766 | 1/20 | 0.41 |
| ▸ | MMP12 | P39900 | 3/20 | 0.40 |
| ▸ | MMP13 | P45452 | 3/20 | 0.40 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4456199 | 0.86 | NPSR1 (0.42) | NPSR1LMNABCAT1ACSL1ACSL6 | |
| SCHEMBL3147148 | 0.83 | LMNA (0.50) | NPSR1LMNABCAT1ACSL1ACSL6 | |
| SCHEMBL7622577 | 0.77 | MMP12 (0.44) | NPSR1LMNABCAT1TTRMMP12 | |
| SCHEMBL26574728 | 0.74 | LMNA (0.52) | NPSR1LMNABCAT1TTRMMP12 | |
| Furobufen SCHEMBL30901203 | 0.74 | CYP1A2 (0.58) | NPSR1LMNABCAT1ACSL1ACSL6 | |
| Furobufen SCHEMBL43450 | 0.74 | CYP1A2 (0.58) | NPSR1LMNABCAT1ACSL1ACSL6 | |
| SCHEMBL8000904 | 0.72 | LMNA (0.47) | NPSR1LMNABCAT1TTRMMP12 | |
| SCHEMBL11485002 | 0.71 | MMP12 (0.52) | LMNAMMP12MMP13NPY5RKMT2A | |
| SCHEMBL30765576 | 0.70 | LMNA (0.41) | NPSR1LMNANPY5RKMT2ASMN1; SMN2 | |
| SCHEMBL7352062 | 0.70 | MMP12 (0.64) | MMP12MMP13KEAP1PTGDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6340709-B1 | ADMINISTERING BIPHENYLSULFONAMIDE DERIVATIVE | WARNER-LAMBERT COMPANY | 2002-01-22 | — | — | US | disclosed |