SCHEMBL4456199

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL7622927	0.86	NPSR1 (0.47)	NPSR1LMNAMMP12MMP13BCAT1
	SCHEMBL3147148	0.77	LMNA (0.50)	NPSR1LMNAMMP12MMP13BCAT1
	SCHEMBL7622577	0.70	MMP12 (0.44)	NPSR1LMNAMMP12MMP13BCAT1
	SCHEMBL15071004	0.69	TTR (0.59)	LMNABCAT1TTRKMT2AMEN1
	SCHEMBL26574728	0.69	LMNA (0.52)	NPSR1LMNAMMP12MMP13BCAT1
	SCHEMBL5819845	0.69	LMNA (0.46)	NPSR1LMNAMMP12MMP13BCAT1
	SCHEMBL11485002	0.69	MMP12 (0.52)	LMNAMMP12MMP13NPY5RCYP3A4
	Furobufen SCHEMBL43450	0.69	CYP1A2 (0.58)	NPSR1LMNABCAT1ACSL1ACSL6
	Furobufen SCHEMBL30901203	0.69	CYP1A2 (0.58)	NPSR1LMNABCAT1ACSL1ACSL6
	SCHEMBL7352062	0.67	MMP12 (0.64)	MMP12MMP13KEAP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.