⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3640721 | 0.85 | — | — | |
| SCHEMBL7266407 | 0.79 | XDH (0.42) | — | |
| SCHEMBL207168 | 0.75 | ALDH1A1 (0.44) | — | |
| SCHEMBL7617381 | 0.73 | — | — | |
| SCHEMBL207428 | 0.71 | ALDH1A1 (0.41) | — | |
| SCHEMBL207131 | 0.71 | ALPL (0.41) | — | |
| SCHEMBL1967417 | 0.71 | KMT2A (0.42) | — | |
| SCHEMBL24214987 | 0.68 | RAD52 (0.30) | — | |
| SCHEMBL28363413 | 0.68 | PRKCI (0.53) | — | |
| SCHEMBL9162899 | 0.67 | NPC1 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1232166-A2 | SYNTHESIS OF 2'-DEOXY-L-NUCLEOSIDES | Pharmasset Limited (US) | 2002-08-21 | — | — | EP | disclosed |
| WO-2001034618-A2 | SYNTHESIS OF 2'-DEOXY-L-NUCLEOSIDES | PHARMASSET LIMITED (US) | 2001-05-17 | — | — | WO | disclosed |