Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 6/20 | 0.34 |
| ▸ | ABCC1 | P33527 | 4/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | LTA4H | P09960 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7629808 | 0.84 | — | — | |
| SCHEMBL7622816 | 0.78 | TSHR (0.36) | ABCB1ABCC1TSHRCYP1A2CYP2C9 | |
| SCHEMBL708763 | 0.77 | LTA4H (0.46) | ABCB1ALDH1A1MGLLTSHRCYP1A2 | |
| SCHEMBL7877836 | 0.76 | ABCB1 (0.34) | ABCB1ABCC1ALDH1A1TSHRHTT | |
| SCHEMBL2874011 | 0.76 | LTA4H (0.46) | ABCB1ALDH1A1MGLLTSHRCYP1A2 | |
| SCHEMBL17391409 | 0.74 | LTA4H (0.44) | ABCB1ALDH1A1MGLLTSHRCYP2C9 | |
| SCHEMBL7869262 | 0.74 | — | — | |
| SCHEMBL7877838 | 0.72 | CA1 (0.30) | — | |
| SCHEMBL7623208 | 0.72 | — | — | |
| SCHEMBL877452 | 0.71 | FAAH (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1218422-A1 | AZIDOSILANE-MODIFIED, MOISTURE-CURABLE POLYOLEFIN POLYMERS, PROCESS FOR MAKING, AND ARTICLES OBTAINED THEREFROM | THE DOW CHEMICAL COMPANY (US) | 2002-07-03 | — | — | EP | disclosed |
| WO-2001010914-A1 | AZIDOSILANE-MODIFIED, MOISTURE-CURABLE POLYOLEFIN POLYMERS, PROCESS FOR MAKING, AND ARTICLES OBTAINED THEREFROM | THE DOW CHEMICAL COMPANY (US) | 2001-02-15 | — | — | WO | disclosed |