SCHEMBL877452

SCHEMBL877452

CCCCCS(=O)(=O)N=[N+]=[N-]

nearest known ligand 0.46

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
FAAH O00519 4/20 0.46
CA2 P00918 6/20 0.38
SGPL1 O95470 4/20 0.32
CES1 P23141 2/20 0.32
CES2 O00748 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27407223 0.98 FAAH (0.50) FAAHCA2CES1CES2
SCHEMBL11705927 0.98 FAAH (0.50) FAAHCA2CES1CES2
SCHEMBL22983945 0.98 FAAH (0.50) FAAHCA2CES1CES2
SCHEMBL27654967 0.98 FAAH (0.50) FAAHCA2CES1CES2
SCHEMBL17111324 0.93 FAAH (0.38) FAAHCA2
Fluoride SCHEMBL28306809 0.91 FAAH (0.37) FAAH
SCHEMBL10359085 0.86 FAAH (0.32) FAAH
SCHEMBL5419555 0.86 FAAH (0.32) FAAH
SCHEMBL180676 0.86 FAAH (0.32) FAAH
SCHEMBL263989 0.86 FAAH (0.32) FAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 202 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3307809-B1 LONG-CHAIN BRANCHED POLYMERS AND PRODUCTION PROCESSES BRASKEM AMERICA INC (US) 2023-06-28 EP claimed
CN-113105493-B Naphthosilole compound and synthesis method for preparing naphthosilole compound through photocatalysis 华南理工大学 2022-03-29 CN claimed
CN-108473454-B A process for the preparation of formula (1) and intermediates therefor 研成精密化学株式会社 2022-03-25 CN claimed
CN-113769776-A Preparation method and application of USY molecular sieve supported reduction metal copper catalyst 西北大学 2021-12-10 CN claimed
CN-113764824-A Battery with separator provided with surface modifier 赛尔格有限责任公司 2021-12-07 CN claimed
CN-113105493-A Naphthosilole compound and synthesis method for preparing naphthosilole compound through photocatalysis 华南理工大学 2021-07-13 CN claimed
EP-2945980-B1 SURFACE-MODIFIED POLYOLEFINIC ARTICLE CELGARD LLC (US) 2021-04-07 EP claimed
EP-3406604-B1 METHOD FOR PREPARING 3-((2S,5S)-4-METHYLENE-5-(3-OXOPROPYL)TETRAHYDROFURANE-2-YL) PROPANOL DERIVATIVE, AND INTERMEDIATE THEREFOR YONSUNG FINE CHEMICAL CO LTD (KR) 2021-03-17 EP claimed
US-10451604-B2 Methods of measuring hydrogen sulfide concentrations in reservoir fluids SHELL OIL COMPANY (US) 2019-10-22 US claimed
US-10240031-B2 Surface modifying agents, modified materials and methods CELGARD, LLC (US) 2019-03-26 US claimed
WO-2016205387-A1 LONG-CHAIN BRANCHED POLYMERS AND PRODUCTION PROCESSES BRASKEM AMERICA, INC. (US) 2016-12-22 WO claimed
US-20160362509-A1 LONG-CHAIN BRANCHED POLYMERS AND PRODUCTION PROCESSES BRASKEM AMERICA, INC. 2016-12-15 US claimed
US-20140206251-A1 SURFACE MODIFYING AGENTS, MODIFIED MATERIALS AND METHODS CELGARD, LLC (US) 2014-07-24 US claimed
US-20110112288-A1 Metal Porphyrin Catalyzed Olefin Aziridination with Sulfonyl Azides UNIVERSITY OF SOUTH FLORIDA (US) 2011-05-12 US claimed
WO-2009146032-A2 METAL PORPHYRIN CATALYZED OLEFIN AZIRIDINATION WITH SULFONYL AZIDES UNIVERSITY OF SOUTH FLORIDA (US) 2009-12-03 WO claimed
WO-2008089005-A2 RENIN INHIBITORS TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2008-07-24 WO claimed
US-20040220413-A1 Method of producing optically active aziridine compounds and amine compounds KYUSHU UNIVERSITY (JP) 2004-11-04 US claimed
EP-1449831-A1 Method of producing optically active aziridine compounds and amine compounds Kyushu University (JP) 2004-08-25 EP claimed
EP-0102893-A1 A novel production of 1-oxacephams SHIONOGI & CO., LTD. (JP) 1984-03-14 EP claimed
US-3998999-A Process for preparing pyrazomycin and pyrazomycin B HOFFMANN-LA ROCHE INC. (US) 1976-12-21 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040220413-A1 Method of producing optically active aziridine compounds and amine compounds AOC2, AZI2, SRM FAAH 3121/4885CA2 3035/4885SGPL1 3825/4885
US-20110112288-A1 Metal Porphyrin Catalyzed Olefin Aziridination with Sulfonyl Azides PPOX, SOD1, AP1S1 FAAH 4534/4885CA2 939/4885SGPL1 3083/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.