SCHEMBL7624672

SCHEMBL7624672

Cn1cncc1-c1c(C(CC#N)c2ccc(Cl)cc2)ccc2c1c(-c1cccc(Cl)c1)cc(=O)n2C

nearest known ligand 0.54

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
FNTA P49354 10/20 0.54
FNTB P49356 10/20 0.54
PGGT1B P53609 5/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5733786 0.70 FNTA (1.00) FNTAFNTB
SCHEMBL13186537 0.70 FNTA (1.00) FNTAFNTB
SCHEMBL7707732 0.69 FNTA (0.76) FNTAFNTBPGGT1B
SCHEMBL13573613 0.68 FNTA (0.81) FNTAFNTB
SCHEMBL3436599 0.68 FNTA (0.81) FNTAFNTB
SCHEMBL28532205 0.68 IDO1 (0.50) FNTAFNTBPGGT1B
SCHEMBL6010160 0.68 FNTA (0.78) FNTAFNTB
Hydrochloric Acid SCHEMBL6010264 0.68 FNTA (0.78) FNTAFNTB
SCHEMBL3847890 0.67 FNTA (0.76) FNTAFNTB
SCHEMBL5516120 0.67 FNTA (0.72) FNTAFNTBPGGT1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020091138-A1 Method of use of (imidazol-5-yl)methyl-2-quinolinone derivatives to inhibit smooth muscle cell proliferation END DAVID WILLIAM (US) 2002-07-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020091138-A1 Method of use of (imidazol-5-yl)methyl-2-quinolinone derivatives to inhibit smooth muscle cell proliferation MYLK, ACTN1, ALK FNTA 4747/4885FNTB 4394/4885PGGT1B 2543/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.