Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.50 |
| ▸ | FNTA | P49354 | 13/20 | 0.44 |
| ▸ | FNTB | P49356 | 13/20 | 0.44 |
| ▸ | PGGT1B | P53609 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7854707 | 0.74 | IDO1 (0.47) | IDO1FNTAFNTBPGGT1B | |
| SCHEMBL5820636 | 0.71 | IDO1 (0.49) | IDO1FNTAFNTBCYP1A2CYP2C9 | |
| SCHEMBL23539669 | 0.69 | IDO1 (1.00) | IDO1FNTAFNTBPGGT1B | |
| SCHEMBL30042691 | 0.69 | IDO1 (1.00) | IDO1FNTAFNTBPGGT1B | |
| SCHEMBL7095527 | 0.69 | IDO1 (0.44) | IDO1FNTAFNTBPGGT1B | |
| SCHEMBL7624672 | 0.68 | FNTA (0.54) | FNTAFNTBPGGT1B | |
| SCHEMBL7115622 | 0.67 | IDO1 (0.42) | IDO1FNTAFNTBPGGT1BCYP1A2 | |
| SCHEMBL28524599 | 0.67 | GABRA5 (0.46) | IDO1 | |
| SCHEMBL6556599 | 0.67 | IDO1 (0.44) | IDO1FNTAFNTBPGGT1B | |
| SCHEMBL7091956 | 0.67 | IDO1 (0.47) | IDO1FNTAFNTBPGGT1BCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112424149-A | Synthesis of tipifarnib | 库拉肿瘤学公司 | 2021-02-26 | — | — | CN | disclosed |