Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9288040 | 0.81 | TP53 (0.40) | MTNR1AMTNR1BSMN1; SMN2OPRM1ALDH1A1 | |
| SCHEMBL27639200 | 0.80 | MEN1 (0.42) | KDM4EL3MBTL1MTNR1AMTNR1BSMN1; SMN2 | |
| SCHEMBL9132125 | 0.79 | KMT2A (0.43) | MTNR1AMTNR1BMEN1KMT2AALDH1A1 | |
| SCHEMBL7994638 | 0.79 | CARM1 (0.42) | MTNR1AMTNR1BSMN1; SMN2MEN1CYP3A4 | |
| SCHEMBL28871165 | 0.79 | MTNR1A (0.46) | MTNR1AMTNR1BSMN1; SMN2MEN1CYP3A4 | |
| SCHEMBL6404340 | 0.78 | ALDH1A1 (0.39) | KDM4EMTNR1AMTNR1BCYP3A4ALDH1A1 | |
| SCHEMBL2215569 | 0.78 | CA4 (0.36) | KDM4EMTNR1AMTNR1BSMN1; SMN2MEN1 | |
| SCHEMBL7921601 | 0.78 | TAAR1 (0.52) | OPRM1 | |
| SCHEMBL11637359 | 0.78 | TDP1 (0.42) | L3MBTL1SMN1; SMN2MEN1KMT2AOPRM1 | |
| SCHEMBL1257089 | 0.76 | TSHR (0.43) | KDM4EL3MBTL1MEN1CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020144355-A1 | Primary intermediates for oxidative coloration of hair | WELLA OPERATIONS US, LLC | 2002-10-10 | — | — | US | claimed |
| CN-1008101-B | PROCESS OF PRODUCTION FOR POLYPHENYL ETHER | ASAHI CHEMICAL IND (JP) | 1990-05-23 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020144355-A1 | Primary intermediates for oxidative coloration of hair | CYC1, CBR1, CBR3 | KDM4E 1002/4885L3MBTL1 3030/4885MTNR1A 272/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.