Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | CLK1 | P49759 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.32 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27629517 | 0.84 | CYP3A4 (0.41) | ALDH1A1CYP3A4TP53CASP1RECQL | |
| SCHEMBL7626883 | 0.78 | KDM4E (0.42) | ALDH1A1CYP3A4TP53RECQLTDP1 | |
| SCHEMBL29375628 | 0.77 | CYP3A4 (0.42) | ALDH1A1CYP3A4TP53CASP1RECQL | |
| SCHEMBL94021 | 0.77 | CYP3A4 (0.42) | ALDH1A1CYP3A4TP53CASP1RECQL | |
| SCHEMBL3725884 | 0.75 | ALDH1A1 (0.49) | ALDH1A1CYP3A4TP53CASP1RECQL | |
| SCHEMBL28883135 | 0.72 | MAOA (0.44) | ALDH1A1CYP3A4CASP1RECQLCA12 | |
| SCHEMBL27744366 | 0.72 | ALDH1A1 (0.48) | ALDH1A1CYP3A4TP53CASP1RECQL | |
| SCHEMBL11679845 | 0.72 | ALDH1A1 (0.40) | ALDH1A1CYP3A4CASP1RECQLCLK1 | |
| SCHEMBL4667347 | 0.71 | ALDH1A1 (0.38) | ALDH1A1CYP3A4TP53CASP1RECQL | |
| SCHEMBL27595402 | 0.70 | PBRM1 (0.36) | ALDH1A1CYP3A4CASP1RECQLCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050005370-A1 | 2-(Amino or substituted amino)-5-(substituted oxymethyl)-phenol compounds, dyeing compositions containing them, and use thereof | THE PROCTER & GAMBLE COMPANY | 2005-01-13 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050005370-A1 | 2-(Amino or substituted amino)-5-(substituted oxymethyl)-phenol compounds, dyeing compositions containing them, and use thereof | KRT18, LOX, TYR | ALDH1A1 422/4885CYP3A4 973/4885TP53 1278/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.