Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.43 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | GMNN | O75496 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | THPO | P40225 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CETP | P11597 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | UBE2N | P61088 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | FDPS | P14324 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3020218 | 0.91 | ALDH1A1 (0.41) | LMNACYP3A4FDPS | |
| SCHEMBL17627171 | 0.91 | GPR84 (0.46) | GPR84SPHK1FFAR1LMNAMAPT | |
| SCHEMBL19216149 | 0.91 | GPR84 (0.46) | GPR84SPHK1FFAR1LMNAMAPT | |
| SCHEMBL4605046 | 0.88 | GPR84 (0.45) | GPR84SPHK1FFAR1LMNAMAPT | |
| SCHEMBL11110178 | 0.86 | GPR84 (0.43) | GPR84SPHK1FFAR1LMNAMAPT | |
| SCHEMBL9580188 | 0.82 | LMNA (0.48) | GPR84SPHK1FFAR1LMNAMAPT | |
| SCHEMBL28236075 | 0.82 | MAPT (0.42) | GPR84SPHK1FFAR1LMNAMAPT | |
| SCHEMBL21551886 | 0.81 | GPR84 (0.46) | GPR84SPHK1FFAR1LMNAMAPT | |
| SCHEMBL21552166 | 0.81 | GPR84 (0.46) | GPR84SPHK1FFAR1LMNAMAPT | |
| SCHEMBL8675412 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6444858-B2 | VAPOR PHASE | BAKER HUGHES INCORPORATED | 2002-09-03 | — | — | US | disclosed |
| EP-0161459-A1 | Alcohol-amine alkoxylates | Conoco Phillips Company (US) | 1985-11-21 | — | — | EP | disclosed |