SCHEMBL4605046

SCHEMBL4605046

CCCCCCC(CCCC)C(O)I

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 7/20 0.45
SPHK1 Q9NYA1 2/20 0.45
FFAR1 O14842 2/20 0.45
LMNA P02545 2/20 0.44
DNM1 Q05193 2/20 0.44
MAPT P10636 2/20 0.43
CYP2D6 P10635 2/20 0.42
GMNN O75496 1/20 0.42
POLB P06746 1/20 0.42
THPO P40225 1/20 0.42
MTOR P42345 1/20 0.42
BLM P54132 1/20 0.42
KDM4E B2RXH2 1/20 0.42
TP53 P04637 1/20 0.42
CYP1A2 P05177 1/20 0.42
CYP3A4 P08684 1/20 0.42
CETP P11597 1/20 0.42
HTT P42858 1/20 0.42
UBE2N P61088 1/20 0.42
CA2 P00918 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19216149 0.98 GPR84 (0.46) GPR84SPHK1FFAR1LMNAMAPT
SCHEMBL17627171 0.98 GPR84 (0.46) GPR84SPHK1FFAR1LMNAMAPT
SCHEMBL11110178 0.93 GPR84 (0.43) GPR84SPHK1FFAR1LMNAMAPT
SCHEMBL7627205 0.88 GPR84 (0.43) GPR84SPHK1FFAR1LMNAMAPT
SCHEMBL9580188 0.84 LMNA (0.48) GPR84SPHK1FFAR1LMNAMAPT
SCHEMBL3020218 0.83 ALDH1A1 (0.41) LMNADNM1CYP3A4CA2
SCHEMBL28234931 0.81 DNM1 (0.44) GPR84SPHK1FFAR1LMNADNM1
SCHEMBL909119 0.80 GPR84 (0.48) GPR84SPHK1FFAR1LMNADNM1
SCHEMBL26122853 0.80 GPR84 (0.48) GPR84SPHK1FFAR1LMNADNM1
SCHEMBL20962950 0.79 DNM1 (0.58) GPR84SPHK1FFAR1LMNADNM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1276553-B2 DISPERSANTS LUBRIZOL CORP (US) 2012-11-07 EP disclosed
EP-1276553-B1 DISPERSANTS LUBRIZOL CORP (US) 2008-07-09 EP disclosed
EP-1702672-A1 Dispersants The Lubrizol Corporation (US) 2006-09-20 EP disclosed