Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.42 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.42 |
| ▸ | ITGAV | P06756 | 1/20 | 0.42 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.42 |
| ▸ | ITGB6 | P18564 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.40 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10657291 | 0.82 | ITGB3 (0.39) | ALDH1A1ITGB3ITGB1ITGAVITGB5 | |
| SCHEMBL3067773 | 0.81 | ALDH1A1 (0.51) | ALDH1A1FFAR1MEN1KMT2AATM | |
| SCHEMBL3078167 | 0.80 | ALDH1A1 (0.46) | ALDH1A1MEN1KMT2AATMRAB9A | |
| SCHEMBL6262756 | 0.79 | ACACB (0.46) | ALDH1A1FFAR1MEN1KMT2AITGB3 | |
| SCHEMBL8070370 | 0.79 | ALDH1A1 (0.53) | ALDH1A1FFAR1MEN1KMT2AATM | |
| SCHEMBL17590406 | 0.78 | MEN1 (0.51) | MEN1KMT2ALMNAL3MBTL1 | |
| SCHEMBL26210906 | 0.78 | MEN1 (0.51) | MEN1KMT2ALMNAL3MBTL1 | |
| SCHEMBL19976457 | 0.78 | ALDH1A1 (0.44) | ALDH1A1LMNAMAPTL3MBTL1 | |
| SCHEMBL3512373 | 0.78 | MEN1 (0.51) | MEN1KMT2ALMNAL3MBTL1 | |
| SCHEMBL10654434 | 0.77 | ITGB3 (0.40) | ALDH1A1ITGB3ITGB1ITGAVITGB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8138168-B1 | Renin inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2012-03-20 | — | — | US | disclosed |