Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 2/20 | 0.39 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.39 |
| ▸ | ITGAV | P06756 | 1/20 | 0.39 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.39 |
| ▸ | ITGB6 | P18564 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CPB2 | Q96IY4 | 5/20 | 0.35 |
| ▸ | KMO | O15229 | 1/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.33 |
| ▸ | CPA1 | P15085 | 2/20 | 0.33 |
| ▸ | CPB1 | P15086 | 1/20 | 0.33 |
| ▸ | CPA3 | P15088 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10654434 | 0.84 | ITGB3 (0.40) | ITGB3ITGB1ITGAVITGB5ITGB6 | |
| SCHEMBL10660780 | 0.82 | ITGB3 (0.37) | ITGB3ITGB1ITGAVITGB5ITGB6 | |
| SCHEMBL762740 | 0.82 | ALDH1A1 (0.49) | ITGB3ITGB1ITGAVITGB5ITGB6 | |
| SCHEMBL10655211 | 0.79 | ALDH1A1 (0.40) | ITGB3ITGB1ITGAVITGB5ITGB6 | |
| SCHEMBL17590406 | 0.75 | MEN1 (0.51) | — | |
| SCHEMBL26210906 | 0.75 | MEN1 (0.51) | — | |
| SCHEMBL3512373 | 0.75 | MEN1 (0.51) | — | |
| SCHEMBL19211563 | 0.74 | NOS2 (0.32) | ALDH1A1 | |
| SCHEMBL6262756 | 0.73 | ACACB (0.46) | ITGB3ITGB1ITGAVITGB5ITGB6 | |
| SCHEMBL15858739 | 0.73 | GABRA1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0295839-A2 | Pyrimidine derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-12-21 | — | — | EP | disclosed |