Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.49 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8070370 | 0.88 | ALDH1A1 (0.53) | ALDH1A1CPB2FFAR1MEN1KMT2A | |
| SCHEMBL9764594 | 0.85 | EPHX1 (0.51) | ALDH1A1CPB2MEN1KMT2AATM | |
| SCHEMBL8061099 | 0.83 | ALDH1A1 (0.48) | ALDH1A1MEN1KMT2AATMRAB9A | |
| SCHEMBL762459 | 0.83 | RAB9A (0.50) | ALDH1A1MEN1KMT2AATMRAB9A | |
| SCHEMBL12241782 | 0.81 | TBXAS1 (0.54) | TBXAS1CPB2FFAR1MEN1KMT2A | |
| SCHEMBL762740 | 0.81 | ALDH1A1 (0.49) | ALDH1A1CPB2FFAR1MEN1KMT2A | |
| SCHEMBL5280916 | 0.80 | HSD17B10 (0.57) | ALDH1A1MEN1KMT2ALMNAPKM | |
| SCHEMBL18057309 | 0.80 | CPB2 (0.68) | TBXAS1CPB2FFAR1 | |
| SCHEMBL7280552 | 0.80 | HSD17B10 (0.57) | ALDH1A1MEN1KMT2ALMNAPKM | |
| SCHEMBL1410549 | 0.79 | TBXAS1 (0.48) | TBXAS1CPB2FFAR1PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1732895-B1 | INSECTICIDAL N-SUBSTITUTED SULFOXIMINES | DOW AGROSCIENCES LLC (US) | 2016-11-16 | — | — | EP | disclosed |
| EP-1732895-B1 | INSECTICIDAL N-SUBSTITUTED SULFOXIMINES | DOW AGROSCIENCES LLC (US) | 2016-11-16 | — | — | EP | disclosed |
| CN-1942442-B | Insecticidal N-substituted sulfenimides | DOW AGROSCIENCES LLC | 2012-10-31 | — | — | CN | disclosed |
| CN-101648906-B | Insecticidal N-substituted sulfoximines | DOW AGROSCIENCES LLC | 2012-07-11 | — | — | CN | disclosed |
| US-7897782-B2 | [3-(6-Chloropyridin-3-yl)-2-methylpropyl](methyl)oxido- lambda 4-sulfanylidenecyanamide; aphidicides | DOW AGROSCIENCES LLC (US) | 2011-03-01 | — | — | US | disclosed |
| US-7897782-B2 | [3-(6-Chloropyridin-3-yl)-2-methylpropyl](methyl)oxido- lambda 4-sulfanylidenecyanamide; aphidicides | DOW AGROSCIENCES LLC (US) | 2011-03-01 | — | — | US | disclosed |
| US-7897782-B2 | [3-(6-Chloropyridin-3-yl)-2-methylpropyl](methyl)oxido- lambda 4-sulfanylidenecyanamide; aphidicides | DOW AGROSCIENCES LLC (US) | 2011-03-01 | — | — | US | disclosed |
| US-7834188-B2 | Insecticidal N-substituted sulfoximines | DOW AGROSCIENCES LLC (US) | 2010-11-16 | — | — | US | disclosed |
| US-7834188-B2 | Insecticidal N-substituted sulfoximines | DOW AGROSCIENCES LLC (US) | 2010-11-16 | — | — | US | disclosed |
| US-7834188-B2 | Insecticidal N-substituted sulfoximines | DOW AGROSCIENCES LLC (US) | 2010-11-16 | — | — | US | disclosed |
| US-20100056578-A1 | INSECTICIDAL N-SUBSTITUTED SULFOXIMINES | DOW AGROSCIENCES LLC (US) | 2010-03-04 | — | — | US | disclosed |
| US-20100056579-A1 | INSECTICIDAL N-SUBSTITUTED SULFOXIMINES | DOW AGROSCIENCES LLC (US) | 2010-03-04 | — | — | US | disclosed |
| US-20100056579-A1 | INSECTICIDAL N-SUBSTITUTED SULFOXIMINES | DOW AGROSCIENCES LLC (US) | 2010-03-04 | — | — | US | disclosed |
| CN-101648906-A | Insecticidal N-substituted sulfoximines | DOW AGROSCIENCES LLC US | 2010-02-17 | — | — | CN | disclosed |
| CN-1942442-A | Insecticidal N-substituted sulfenimides | DOW AGROSCIENCES LLC (US) | 2007-04-04 | — | — | CN | disclosed |
| EP-1732895-A2 | INSECTICIDAL N-SUBSTITUTED SULFOXIMINES | Dow Agrosciences LLC (US) | 2006-12-20 | — | — | EP | disclosed |
| WO-2006060029-A2 | INSECTICIDAL N-SUBSTITUTED SULFOXIMINES | DOW AGROSCIENCES LLC (US) | 2006-06-08 | — | — | WO | disclosed |
| US-20050228027-A1 | Insecticidal N-substituted sulfoximines | CORTEVA AGRISCIENCE LLC | 2005-10-13 | — | — | US | disclosed |
| EP-1021409-A1 | HETEROCYCLIC COMPOUNDS AS PESTICIDES | Novartis AG (CH) | 2000-07-26 | — | — | EP | disclosed |
| WO-1999012906-A1 | HETEROCYCLIC COMPOUNDS AS PESTICIDES | NOVARTIS AG (CH) | 1999-03-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100056579-A1 | INSECTICIDAL N-SUBSTITUTED SULFOXIMINES | GSS, STS, SMS | ALDH1A1 3325/4885TBXAS1 1535/4885CPB2 2648/4885 |
| US-20100056578-A1 | INSECTICIDAL N-SUBSTITUTED SULFOXIMINES | GSS, STS, SMS | ALDH1A1 3325/4885TBXAS1 1535/4885CPB2 2648/4885 |
| US-20050228027-A1 | Insecticidal N-substituted sulfoximines | GSS, STS, SMS | ALDH1A1 3325/4885TBXAS1 1535/4885CPB2 2648/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.