Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 8/20 | 0.36 |
| ▸ | MMP1 | P03956 | 4/20 | 0.36 |
| ▸ | ADAM17 | P78536 | 4/20 | 0.36 |
| ▸ | MMP9 | P14780 | 5/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | HTR7 | P34969 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | METAP2 | P50579 | 1/20 | 0.30 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6801890 | 0.90 | MMP13 (0.36) | MMP13MMP1ADAM17MMP9MMP2 | |
| SCHEMBL6934658 | 0.78 | MMP1 (0.49) | MMP13MMP1ADAM17MMP9 | |
| SCHEMBL6930067 | 0.77 | MMP13 (0.50) | MMP13MMP1ADAM17MMP9ALDH1A1 | |
| SCHEMBL7619177 | 0.77 | MMP13 (0.32) | MMP13MMP1ADAM17MMP9MMP2 | |
| SCHEMBL6930141 | 0.76 | MMP1 (0.36) | MMP13MMP1MMP9MMP2FFAR1 | |
| SCHEMBL6932872 | 0.75 | MMP1 (0.49) | MMP13MMP1ADAM17MMP9 | |
| SCHEMBL6933389 | 0.73 | MMP13 (0.53) | MMP13MMP1ADAM17MMP9MMP2 | |
| SCHEMBL6934875 | 0.72 | MMP13 (0.46) | MMP13MMP1ADAM17MMP9MMP2 | |
| SCHEMBL6800697 | 0.70 | GPR119 (0.39) | MMP13MMP1ADAM17MMP2ALDH1A1 | |
| SCHEMBL22951407 | 0.68 | ALDH1A1 (0.44) | HTR7FFAR1FFAR4ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6444685-B1 | THERAPY FOR METABOLISM DISEASES; DIETETICS; ANTIDIABETIC AGENTS | WYETH | 2002-09-03 | — | — | US | disclosed |